2. For each DNA repair process in column I, list all characteristics from column II that correctly describe that process. I II 1. RecA protein participates. 2. Damaged nucleotides are removed by nick translation (a) Nucleotide excision repair (b) Photoreactivation (c) Base excision repair (d) Recombinational repair (e) SOS-driven error-prone repair (f) Alkyltransferase repair (g) Mismatch repair (h) Double-strand break repair 3. A free radical mechanism is involved. 4. The repair enzyme functions only once. 5. The key enzyme contains a bound folate cofactor. 6. No bases or nucleotides are removed from the DNA. 7. Deficiency of this enzyme in humans greatly increases the risk of skin cancer. 8. This system is chiefly responsible for the mutagenic effect of ultraviolet light. 9. The first enzyme in this pathway cleaves two phosphodiester bonds. 10. This process begins up to 1 kbp away from the site to be repaired. 11. DNA ligase catalyzes the final reaction. 12. This process also occurs in meiotic recombination. 13. Replication fork regression might occur during this process.

2. For each DNA repair process in column I, list all characteristics from column II that correctly describe that process. I II 1. RecA protein participates. 2. Damaged nucleotides are removed by nick translation (a) Nucleotide excision repair (b) Photoreactivation (c) Base excision repair (d) Recombinational repair (e) SOS-driven error-prone repair (f) Alkyltransferase repair (g) Mismatch repair (h) Double-strand break repair 3. A free radical mechanism is involved. 4. The repair enzyme functions only once. 5. The key enzyme contains a bound folate cofactor. 6. No bases or nucleotides are removed from the DNA. 7. Deficiency of this enzyme in humans greatly increases the risk of skin cancer. 8. This system is chiefly responsible for the mutagenic effect of ultraviolet light. 9. The first enzyme in this pathway cleaves two phosphodiester bonds. 10. This process begins up to 1 kbp away from the site to be repaired. 11. DNA ligase catalyzes the final reaction. 12. This process also occurs in meiotic recombination. 13. Replication fork regression might occur during this process.

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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2b) Suppose you generated a mutant E. coli strain in which it was DNA Polymerase I that was inactivated - assuming that all the other enzymes involved in replication remained fully functional, how would DNA replication in these mutant cells lacking DNA Pol I differ from DNA replication in normal E. coli? Briefly explain why you would expect to see that change/those changes in DNA replication in the mutant cells.
Which of the following DNA repair pathways repair DNA double strand breakage that only occur in diving cells?. Please select all correct answers. A. Nucleotide excision repair (NER) B. Mismatch repair (MMR) C. Double- strand break repair(DSBR) D.non- homologous end joining (NHEJ) E. Synthesis-dependent strand annealing(SDSA)
2. What is the difference between the old and the new DNA strands? 3. What process invoives the production of MRNA using DNA as template? 1. In the Central Dogma, what process involves the production of a new DNA strand using an old DNA strand as blueprint or template? * How is replication different from transcription in terms of product? 5 What do you call each triplet code made up of three linearly arranged nucleotides in the MRNA? 6 What is the complement of the mRNA tripiet code in the tRNA? 7 In what way is tRNA different from MRNA? 8 In what ways are RNA and DNA similar? 9. In what ways are they different?
For each DNA repair process in column I, list all characteristics fromcolumn II that correctly describe that process.I(a) Nucleotide excision repair(b) Photoreactivation(c) Base excision repair(d) Recombinational repair(e) SOS-driven error-prone repair(f) Alkyltransferase repair(g) Mismatch repair(h) Double-strand break repairII1. RecA protein participates.2. Damaged nucleotides are removed by nick translation.3. A free radical mechanism is involved.4. The repair enzyme functions only once.5. The key enzyme contains a bound folate cofactor.6. No bases or nucleotides are removed from the DNA.7. Deficiency of this enzyme in humans greatly increases the risk of skincancer.8. This system is chiefly responsible for the mutagenic effect of ultravioletlight.9. This process begins with cleavage of two phosphodiester bonds.10. This process begins up to 1 kbp away from the site to be repaired.11. DNA ligase catalyzes the final reaction.12. This process also occurs in meiotic recombination.13.…
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1. Illustrate, Consider the given pair of homologous DNA molecules. W X Y Z W' X' Y' Z' w' W y Suppose the single stand breaks shown in the figure initiated an exchange of segments and branch migration proceeded up to the Y'-Z' region. Following the color-coding and genotypes of the given DNA molecules, a. draw the resulting DNA molecule after branch migration. Do not forget to show the Holliday junction.
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Below is a study of a colony of cells, determine that some of these cells have a mutated DNA polymerase I that results in loss of function of this enzyme. - What will the effect of the mutation in DNA polymerase I be on DNA replication? Include leading and lagging strand - Will this mutation in DNA polymerase I have an impact on another step in DNA replication? Will DNA be replicatation be impacted? Are any enzymes involved?
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3. 1. 2. Given the structure below, identify (name) and explain what modifications you observe considering that this base is normally found in DNA. Identify what type of DNA repair pathway you expect would recognize and correct this DNA damage. Use the numbered positions to describe the modifications to the molecule. но 2 Но. H.