2) Glycogen phosphorylase catalyzes the breakdown of glycogen. A) What is the reaction catalyzed by glycogen phosphorylase? B) What are TWO ways (modes of regulation) that the activity of glycogen phosphorylase is controlled- at the level of the enzyme? C) What TWO hormones control the level of activity of glycogen phosphorylase, and WHAT EFFECT (increase/decrease) do these two hormones have on the activity of glycogen phosphorylase? D) Explain how the above listed factors affect the activity of glycogen phosphorylase - at the level of the enzyme. E) Glucagon drives phosphorylation of glycogen phosphorylase and inhibits dephosphorylation. Explain.

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
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Chapter4: Principles Of Neural And Hormonal Communication
Section4.6: Introduction To Paracrine Communication
Problem 2CYU: Discuss the roles of phospholipase A2, cyclooxygenase, and lipooxygenase.
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2) Glycogen phosphorylase catalyzes the breakdown of glycogen.
A) What is the reaction catalyzed by glycogen phosphorylase?
B) What are TWO ways (modes of regulation) that the activity of glycogen phosphorylase is controlled – at the level
of the enzyme?
C) What TWO hormones control the level of activity of glycogen phosphorylase, and WHAT EFFECT
(increase/decrease) do these two hormones have on the activity of glycogen phosphorylase?
D) Explain how the above listed factors affect the activity of glycogen phosphorylase - at the level of the enzyme.
E) Glucagon drives phosphorylation of glycogen phosphorylase and inhibits dephosphorylation. Explain.
Transcribed Image Text:2) Glycogen phosphorylase catalyzes the breakdown of glycogen. A) What is the reaction catalyzed by glycogen phosphorylase? B) What are TWO ways (modes of regulation) that the activity of glycogen phosphorylase is controlled – at the level of the enzyme? C) What TWO hormones control the level of activity of glycogen phosphorylase, and WHAT EFFECT (increase/decrease) do these two hormones have on the activity of glycogen phosphorylase? D) Explain how the above listed factors affect the activity of glycogen phosphorylase - at the level of the enzyme. E) Glucagon drives phosphorylation of glycogen phosphorylase and inhibits dephosphorylation. Explain.
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