12 If you go into your local grocery store, you are bound to find a host of gluten-free products made with syntheticproteins instead of the natural wheat-based protein gluten. About 1–3% of the population is sensitive to gluten. Themost severe form of gluten intolerance is the autoimmune disease celiac disease (note that it is not caused by gluten,and you cannot get it from eating gluten). In individuals with celiac disease, the immune response to gluten antigenscauses the flattening of the villi in the small intestine. How would this affect the ability of the small intestine tofunction? Predict the symptoms you would expect to see from celiac disease.

Celiac disease is also known as non-tropical sprue, celiac sprue and gluten-sensitive enteropathy.…

Answered: 12 If you go into your local grocery…

Phlebotomy Essentials

6th Edition

ISBN:9781451194524

Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Chapter1: Phlebotomy: Past And Present And The Healthcare Setting

Section: Chapter Questions

Problem 1SRQ

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BONUS QUESTION! In neurons, the proteolytic enzyme y-secretase produces the Aß amyloid peptides shown below. The AB40 peptide is thought to play a protective role in the neuron. However, the AB42 peptide appears to be toxic since it is found in the amyloid plaques that cause Alzheimer's Disease (AD). AB40 and AB42 are identical, except that AB42 contains two extra amino acid residues (shown in red) at the C-terminal end. Based on your knowledge of amino acids and proteins, which of the following factors is most likely to explain the greater plaque-forming activity of AB42 compared to AB40? Sequence of Aß40: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV Sequence of AB42: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA O The greater length of AB42 makes it more likely to aggregate and form plaques. O AB42 has a lower pl than AB40, which makes it more likely to aggregate at physiological pH. O AB42 is more hydrophobic than AB40, which makes it harder to clear from the cell and thus more likely to…
Based on the 2020-25 Dietary Guidelines, what is the % Daily Value for fiber for a strawberry-banana smoothie with 7 grams of fiber? The first step is to identify the Daily Value for fiber, which is grams. The next step is to divide the amount of fiber in the smoothie grams by the Daily Value for fiber. Then, multiply by 100 to get the % Daily Value of % (type in the numbers only, no units, and round to the nearest whole number).
I. A protein, X, was Isolated from a pathogenlc mlcroorganism. The proteln Is a vlrulence factor whose path0genlclty lies In a heptapeptide of unknown sequence. After trypsin cleavage of the heptapeptide from protein X, the peptlde's compOsition and sequence was determined. The fOllowing were the results of the sequenclng process: 1. When the peptide was treated with dinitrofluorobenzene (DNFB), DNP-asp and a mixture of amino acids were produced. 2. When the same Intact peptide was treated with streptococcal protease, a pentapeptide of composition asp, asN, cys, gly and ser and 2 amlno acids were released. 3. When the heptapeptlde was also treated with hydrOxylamine HCI, a tripeptide and a tetrapeptide were obtained. The C-terminal amino acid of the tripeptide was asN. 1) What is the sequence of the heptapeptide if it is composed of cys, asp, lys, asN, gly and ser only? 2) What is the pl of the heptapeptide?
A chain NH3 NH3 B chain Gly Phe 2. The protein pictured below is bovine insulin. Determine the number and the size of the fragments that would be generated upon treatment with the following: İle Val Val Asn Gln Gln 5 Ġln 5 His look for the cleavage points (a) without DTT and (b) with DTT. Cys Leu Cys S-S Cys Without DTT With DTT Ala Ģly Ser Ser Trypsin 10 Val 10 His Cys Leu Chymotrypsin Ser Val Leu Glu BrCN Tyr Ala 15 Gln 15 Leu Leu Тyr Ġlu Leu Ásn Val Тyr Cys 20 Çys 20 Gly Asn Glu Arg Reagent (source) Trypsin (bovine pancrease) Chymotrypsin (bovine pancrease) Staphylococcus V8 protease Pepsin (porcine pancrease) Cyanogen bromide (chemical)(CnBr) Specificity Lys, Arg (C) Phe, Trp, Tyr (C) Glu, Asp (C) Phe, Trp, Tyr (N) Met (C) Gly Phe 25 Phe Тyr Thr Pro Lys 30 Ála
VI. Although most biologically relevant sugars have the D-configuration, L-fucose is a commonly observed monosaccharide component in glycoproteins. Glycosylated antibodies (IgGs) observed in patients with active TB have more fucose than those found in patients with latent TB (Lu et. al., 2016). Latent TB occurs when a person has the TB bacteria, but bacterial proliferation is kept under control by the body's immune system; hence, the infected person is asymptomatic and not infectious. A person with latent TB will test positive for the tuberculin test or TB blood test. a) L-fucose is also known as 6-deoxy-L-galactose. Note that D-galactose is a C-4 epimer of D-glucose. Draw the Fisher projections for D-glucose, D-galactose and L-fucose. (Hints: D- and L-isomers are enantiomers. 6-deoxy means that the hydroxyl group at C-6 is removed leaving just the methyl group). D-galactose: D-glucose: L-fucose (6-deoxy-L-galactose): b) L-fucose can cyclize into a pyranose and form two anomers. Draw…
P CO HI F. sum21.ex1.137 Accessibility Mo 日- Which of the following molecules generally possesses a complex shape that allows the molecule to function as tools and machinery that essentially do all the work within a living cell? 15. A. triglycerides B. proteins C. carbohydrate D. A and Bare correct. 16. Which of the following molecules is NOT involved in cell-to-cell signaling? A nroctaalandine Give %00% kidomi 56°F 近 Insert F8 F6 & %24 8. K 2 G oW N M
4. Ensuring adequate maternal intake of a spe- cific nutrient is especially important in reduc- ing the incidence of the congenital anomaly shown in the image. A deficiency of this nu- trient, when present in an adult, is associated with which of the following conditions? Subarachnoid space (A) Confabulation and anterograde amnesia (B) Diarrhea, dermatitis, and dementia (C) Megaloblastic anemia (D) Megaloblastic anemia with neurologic symptoms (E) Microcytic anemia (F) Polyneuritis and cardiac pathology (G) Swollen and bleeding gums, easy bruising, and poor wound healing HELR
Identify the correct matched protein related disorder * (Please choose one correct answer only) A. Kwashiorkor: prominent presence of edema due to protein and calorie deficiency B. Prion disease occurs due to the presence of tau proteins causing neurofibrillary tangles inside neurons C. Sickle cell anemia as an example of a point mutation replacing glutamic acid with valine and lysine in one of the beta chains of hemoglobin D. Ehlers-Danlos syndrome and Osteogenesis Imperfecta may share the same defects of on the type of fibril forming collagen of the gene
36. Amino acids are not stored in the body. Describe howexcess amino acids are processed in the cell.
2 The following strain of cells lack one enzyme in metabolic pathway. Which of the following strain can grow on glucose under both aerobic and anaerobic conditions, although it grows slower than normal cells under aerobic condition? Explain (less than 100 words). A strain: lack glyceraldehyde-3-phosphate dehydrogenase B strain: lack lactate dehydrogenase C strain: lack pyruvate dehydrogenase
group)? 9. Probability of finding prolines in ẞ-turns are much more in comparison to a-helices or ẞ-sheets. Why?
1. Draw the Fisher projection of D-glucose, and from Fisher to Haworth projection of ẞ-D-glucose. Label (R) and (S) configuration for each chiral carbon Fisher projection Haworth projection

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