10.52 A food-frequency questionnaire is used to measure dietary intake. The respondent specifies the number of servings of various food items he or she consumed over the previous week. The dietary cholesterol is then quantified for each respondent. The researchers were inter- ested in assessing if there was an association between dietary cholesterol intake and high blood pressure. In a large sample of individuals who had completed the questionnaire, 250 persons with a high dietary cholesterol intake (greater than 300 mg/day) were selected, and 250 persons with a low dietary cholesterol intake (less than 300 mg/day) were selected. The 500 selected participants had their medical histories taken and were classified as having normal or high blood pressure. The data are given here. Dietary Cholesterol High Low Total Blood Pressure High 159 78 237 Low 91 172 263 Total 250 250 500 a. Compute the difference in the estimated risks of having high blood pressure (#₁ - #₂) for the two groups (low versus high dietary cholesterol intake). b. Compute the estimated relative risks of having high blood pressure groups (low versus high dietary cholesterol intake). for the two c. Compute the estimated odds ratio of having high blood pressure for the two groups (low versus high dietary cholesterol intake). d. Based on your results from parts (a) (c), how do the two groups compare?

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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**Dietary Cholesterol and Blood Pressure Study**

**10.52** A food-frequency questionnaire is utilized to assess dietary intake concerning cholesterol and its potential relationship with blood pressure. Respondents report their weekly consumption of various food items, allowing researchers to quantify dietary cholesterol for each individual. The objective is to determine if there's an association between dietary cholesterol intake and high blood pressure.

**Study Details:**
- A sample size of 500 participants was divided equally:
  - 250 with high dietary cholesterol intake (greater than 300 mg/day).
  - 250 with low dietary cholesterol intake (less than 300 mg/day).
- Participants were classified based on their medical histories into two categories: high or low blood pressure.

**Data Table:**

| Dietary Cholesterol | Blood Pressure |
|---------------------|------------------------|
|                     | High   | Low   | Total |
| High                | 159    | 91    | 250   |
| Low                 | 78     | 172   | 250   |
| Total               | 237    | 263   | 500   |

**Analysis Tasks:**
a. **Risk Difference:** Calculate the difference in estimated risks of high blood pressure between the two dietary cholesterol groups.

b. **Relative Risk:** Compute the estimated relative risks of high blood pressure for both groups.

c. **Odds Ratio:** Determine the odds ratio for high blood pressure between the groups.

d. **Comparison:** Evaluate and compare the findings from parts (a) to (c) concerning both groups. 

This study aims to provide insights into how dietary cholesterol may influence blood pressure, which is crucial for developing dietary recommendations and managing cardiovascular health.
Transcribed Image Text:**Dietary Cholesterol and Blood Pressure Study** **10.52** A food-frequency questionnaire is utilized to assess dietary intake concerning cholesterol and its potential relationship with blood pressure. Respondents report their weekly consumption of various food items, allowing researchers to quantify dietary cholesterol for each individual. The objective is to determine if there's an association between dietary cholesterol intake and high blood pressure. **Study Details:** - A sample size of 500 participants was divided equally: - 250 with high dietary cholesterol intake (greater than 300 mg/day). - 250 with low dietary cholesterol intake (less than 300 mg/day). - Participants were classified based on their medical histories into two categories: high or low blood pressure. **Data Table:** | Dietary Cholesterol | Blood Pressure | |---------------------|------------------------| | | High | Low | Total | | High | 159 | 91 | 250 | | Low | 78 | 172 | 250 | | Total | 237 | 263 | 500 | **Analysis Tasks:** a. **Risk Difference:** Calculate the difference in estimated risks of high blood pressure between the two dietary cholesterol groups. b. **Relative Risk:** Compute the estimated relative risks of high blood pressure for both groups. c. **Odds Ratio:** Determine the odds ratio for high blood pressure between the groups. d. **Comparison:** Evaluate and compare the findings from parts (a) to (c) concerning both groups. This study aims to provide insights into how dietary cholesterol may influence blood pressure, which is crucial for developing dietary recommendations and managing cardiovascular health.
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