10. Conformational Analysis Consider the two isomeric alkyl halides shown below. When treated with a strong base (e.g. LDA or sodium methoxide) which isomer will undergo elimination the fastest? Put a box around your final answer and explain your reasoning using conformational analysis Hint: I expect to see chair cyclohexanes. Br Br A В

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**10. Conformational Analysis**

Consider the two isomeric alkyl halides shown below. When treated with a strong base (e.g., LDA or sodium methoxide) which isomer will undergo elimination the fastest? Put a box around your final answer and explain your reasoning using conformational analysis.

*Hint: I expect to see chair cyclohexanes.*

[Diagram of two cyclohexane structures]

- **Structure A**: A cyclohexane ring with a bromine (Br) substituent in the axial position. There are also additional methyl groups attached to the ring.
  
- **Structure B**: A cyclohexane ring with a bromine (Br) substituent in the equatorial position. Other methyl groups are attached to the ring as well.
Transcribed Image Text:**10. Conformational Analysis** Consider the two isomeric alkyl halides shown below. When treated with a strong base (e.g., LDA or sodium methoxide) which isomer will undergo elimination the fastest? Put a box around your final answer and explain your reasoning using conformational analysis. *Hint: I expect to see chair cyclohexanes.* [Diagram of two cyclohexane structures] - **Structure A**: A cyclohexane ring with a bromine (Br) substituent in the axial position. There are also additional methyl groups attached to the ring. - **Structure B**: A cyclohexane ring with a bromine (Br) substituent in the equatorial position. Other methyl groups are attached to the ring as well.
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