1. What volume of sterile water for injection (diluent) must be added to reconstitue the powder? 2. How many mL of the reconstituted cefazolin is needed to prepare the final product?

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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1. What volume of sterile water for injection (diluent) must be added to reconstitue the powder?

2. How many mL of the reconstituted cefazolin is needed to prepare the final product?

Preparation of Parenteral Solution
Parenteral drug products should be SHAKEN WELL when reconstituted, and inspected visually for particulate
matter prior to administration. If particulate matter is evident in reconstituted fluids, the drug solutions should
be discarded.
When reconstituted or diluted according to the instructions below, Cefazolin for Injection is stable for 24 hours
at room temperature or for 10 days if stored under refrigeration (5°C or 41°F). Reconstituted solutions may
range in color from pale yellow to yellow without a change in potency.
Single-Dose Vials
For IM injection, IV direct (bolus) injection or IV infusion, reconstitute with Sterile Water for Injection
according to the following table. SHAKE WELL.
Vial Size Amount of Diluent Approximate Concentration Approximate Available Volume
500 mg
1 gram
2 mL
2.5 mL
225 mg/mL
330 mg/mL
2.2 mL
3 mL
Transcribed Image Text:Preparation of Parenteral Solution Parenteral drug products should be SHAKEN WELL when reconstituted, and inspected visually for particulate matter prior to administration. If particulate matter is evident in reconstituted fluids, the drug solutions should be discarded. When reconstituted or diluted according to the instructions below, Cefazolin for Injection is stable for 24 hours at room temperature or for 10 days if stored under refrigeration (5°C or 41°F). Reconstituted solutions may range in color from pale yellow to yellow without a change in potency. Single-Dose Vials For IM injection, IV direct (bolus) injection or IV infusion, reconstitute with Sterile Water for Injection according to the following table. SHAKE WELL. Vial Size Amount of Diluent Approximate Concentration Approximate Available Volume 500 mg 1 gram 2 mL 2.5 mL 225 mg/mL 330 mg/mL 2.2 mL 3 mL
Cefazolin 15 mg/mL
50 mL
Cefazolin (1 gm powder for injection)_750 mg
Sodium Chloride 0.9%
50 mL
Tech:
Made:
B
CEFAZOLIN
for Injection, USP
1 gram
19
For IM or IV Use
RPh:
Expires:
[Cefazolin 1gm powder for injection package insert]
Transcribed Image Text:Cefazolin 15 mg/mL 50 mL Cefazolin (1 gm powder for injection)_750 mg Sodium Chloride 0.9% 50 mL Tech: Made: B CEFAZOLIN for Injection, USP 1 gram 19 For IM or IV Use RPh: Expires: [Cefazolin 1gm powder for injection package insert]
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