1. What volume of sterile water for injection (diluent) must be added to reconstitue the powder?2. How many mL of the reconstituted cefazolin is needed to prepare the final product? Preparation of Parenteral SolutionParenteral drug products should be SHAKEN WELL when reconstituted, and inspected visually for particulatematter prior to administration. If particulate matter is evident in reconstituted fluids, the drug solutions shouldbe discarded.When reconstituted or diluted according to the instructions below, Cefazolin for Injection is stable for 24 hoursat room temperature or for 10 days if stored under refrigeration (5°C or 41°F). Reconstituted solutions mayrange in color from pale yellow to yellow without a change in potency.Single-Dose VialsFor IM injection, IV direct (bolus) injection or IV infusion, reconstitute with Sterile Water for Injectionaccording to the following table. SHAKE WELL.Vial Size Amount of Diluent Approximate Concentration Approximate Available Volume500 mg1 gram2 mL2.5 mL225 mg/mL330 mg/mL2.2 mL3 mL Cefazolin 15 mg/mL50 mLCefazolin (1 gm powder for injection)_750 mgSodium Chloride 0.9%50 mLTech:Made:BCEFAZOLINfor Injection, USP1 gram19For IM or IV UseRPh:Expires:[Cefazolin 1gm powder for injection package insert]

For the 500mg vial :For the 500mg cefazolin vial, we have 2ml of diluent, and the concentration…

Answered: 1. What volume of sterile water for…

1. What volume of sterile water for injection (diluent) must be added to reconstitue the powder? 2. How many mL of the reconstituted cefazolin is needed to prepare the final product?

Phlebotomy Essentials

6th Edition

ISBN:9781451194524

Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Chapter1: Phlebotomy: Past And Present And The Healthcare Setting

Section: Chapter Questions

Problem 1SRQ

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Question

1. What volume of sterile water for injection (diluent) must be added to reconstitue the powder?

2. How many mL of the reconstituted cefazolin is needed to prepare the final product?

Preparation of Parenteral Solution
Parenteral drug products should be SHAKEN WELL when reconstituted, and inspected visually for particulate
matter prior to administration. If particulate matter is evident in reconstituted fluids, the drug solutions should
be discarded.
When reconstituted or diluted according to the instructions below, Cefazolin for Injection is stable for 24 hours
at room temperature or for 10 days if stored under refrigeration (5°C or 41°F). Reconstituted solutions may
range in color from pale yellow to yellow without a change in potency.
Single-Dose Vials
For IM injection, IV direct (bolus) injection or IV infusion, reconstitute with Sterile Water for Injection
according to the following table. SHAKE WELL.
Vial Size Amount of Diluent Approximate Concentration Approximate Available Volume
500 mg
1 gram
2 mL
2.5 mL
225 mg/mL
330 mg/mL
2.2 mL
3 mL

Cefazolin 15 mg/mL
50 mL
Cefazolin (1 gm powder for injection)_750 mg
Sodium Chloride 0.9%
50 mL
Tech:
Made:
B
CEFAZOLIN
for Injection, USP
1 gram
19
For IM or IV Use
RPh:
Expires:
[Cefazolin 1gm powder for injection package insert]

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