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- 4. Peptidyl transferase activity... True False i. catalyzes peptide bond formation. ii. is an enzymatic function of proteins found in the large ribosomal subunit. iii. joins amino acids on tRNAs in the P and E site of the ribosome. iv. requires GTP hydrolysis by the elongation factor.1. The SRP is recognized by the SRP receptor. 2. The ribosome translates the protein through the translocon and into the ER lumen. 3. The ribosome attaches to the translocon. 4. Chaperones assist in the proper folding of the protein. 5. The signal peptide on the nascent polypeptide is synthesized by the ribosome and recognized by the SRP (signal recognition protein). A. 5, 3, 1, 2, 4 OB. 1, 5, 4, 3, 2 C. 5, 1, 3, 2, 4 OD. 1, 2, 3, 4, 5 E. 1, 5, 3, 2, 4 QUESTION 32 The side of the Golgi stack orientated towards the endoplasmic reticulum is the OA. cis-Golgi network B. trans-Golgi network OC. vesicle OD. medial-Golgi QUESTION 33 Which molecule is displaced when a vesicle and its target membrane fuse? A. Water OB. Cholesterol OC. Phospholipids D. DNA OE. SNARES 2. 2.Beta-lactam antibiotics work by? O A. cleaving peptide side chains O B. preventing cross-linking of the peptide side chains by transpeptidase O C. cleaving the 1,4 beta-glycosidic bond between the NAM and NAG © D. inhibiting the action of bactoprenol O E. preventing peptidoglycan from being flipped to the external side of the plasma membrane
- Which of the following statements about ribosomes is correct? * a. the number of ribosomes in a cell seldom exceeds 50 b. the active site of a ribosome contains mostly protein molecules c. structurally, ribosomes have two rRNA- protein subinuts d. no correct response What is the complementary hnRNA base sequence produced from the DNA base sequence 5' C-T-A-T-A-C 3' ? * a. 3' C-T-A-G-A-T 5' b. 3' C-G-G-A-T-A 5' c. 3' G-A-U-A-U-G 5' d. 3' G-A-T-A-T-G 5' The product of the first phase in protein synthesis is * a. DNA molecules b. RNA molecules c. both RNA and DNA molecules d. neither RNA and DNA moleculesmutate all of your D-form amino acids in your peptidoglycan peptide side chains to L forms. What have just done to your peptidoglycan? • A. You prevent lysozyme from being able to work • B. You prevent NAM and NAG from linking together C. You have made it susceptible to degradation by proteases • D. You prevent it from being flipped from the cytoplasm across the plasma membrane O E. Nothing, there is no difference between the L and D forms of amino acidsPoliovirus contains a protein that possesses an NLS. A drug is developed that binds and hides this sequence on the viral protein. What happens to this viral protein, in the presence of the drug? Select all that are true. a. The viral protein is now found in the cytoplasm O b. The viral protein is found in the endomembrane system Oc. The viral protein is secreted O d. The viral protein is found in the ER O e. The viral protein can now enter the nucleus
- 20. The image above reveals two bacterial cells in the process of A. cell lysis B. transduction C. conjugation D. transformation -NAM-NAG-NAM-NAG D-Glu D-Ala D/ Transpeptidase D-Ala DAP T 1 D-Ala D-Glu L-Ala NAG-NAM-NAG-NAM FYRET E. budding K 21. Modification of the enzyme pictured (above) might result in resistance to A. quinolone B. streptomycin C. chloramphenicol D. penicillin E. trimethoprim59. Identify a FALSE statement from following regarding diptheria toxin, Group of answer choices it's is encoded by chromosomal DNA it induces pseudomembrane formation it's is a AB type toxin acidic pH of the endosome, dissociates the A subunit from the B portion targets primarily the respiratory tract epithelial cells 60. It's recommended to take Calcium supplements, especially for elderly women who are prone to developing osteoporosis when taking ...................... Group of answer choices sulfa drugs penicillin none of the above some of the above streptomycin ciprofloxacillinX
- Choose the statement that best describes how proteins move between different compartments within the secretory and endocytic pathways. O A. proteins exit their primary location via translocators and are transported to their next destination by SRP B. proteins are directly translated into the cellular compartment that will serve as their final destination O C. proteins are packaged in vesicles that bud out of one membrane and fuse with the membrane at the next destination O D. proteins diffuse through the membrane where they originated and are bound by chaperones who transport them to their next destination9. In which cellular compartments does mucin-type O-glycan biosynthesis occur in mammalian cells? Select all that apply. a. ER b. Golgi c. Plasma Membrane d. Mitochondria e. Nucleus 10. Identify the five nucleotide sugars NOT FOUND in animal cells. UDP-Glc UDP-GlcNAc UDP-Man UDP-Gal CMP-Fuc UDP-IdoA UDP-Xyl GDP-GalNAc CMP-Sia GDP-GlcA 11. Name at least two factors that determine glycan diversity during their biosynthesis. Availability of nucleotide sugars Expression of glycosyltransferases Nucleotide sugar biosynthetic enzymes The types and abundance of glycosyltransferases Flux through the ER and GolgiWhat molecule tags proteins for destruction by the proteasome? a. lysine b. ubiquitin c. oxaloacetate d. ferrodoxin e. ATP
