1. The lab mentions using an alternative synthetic route, involving the more traditional Friedel- Crafts method of using an alkyl halide. The Friedel Crafts alkylation, using ferric chloride, proceeds as follows: Firstly, a carbocation is formed from the alkyl halide. Secondly, the alkyl cation reacts with a benzene ring, with a subsequent regeneration of the ferric chloride catalyst. CI R-CI + FeCl, R* + FeCl, Ci-Fe-ci R R H - HCI catalyst reganerated Give the reaction mechanism that would produce the 1,4-di-tert-butyl-2,5-dimethoxybenzene, via a Friedel-Crafts alkylation using tert-butyl chloride, ferric chloride and 1,4- dimethoxybenzene.
1. The lab mentions using an alternative synthetic route, involving the more traditional Friedel- Crafts method of using an alkyl halide. The Friedel Crafts alkylation, using ferric chloride, proceeds as follows: Firstly, a carbocation is formed from the alkyl halide. Secondly, the alkyl cation reacts with a benzene ring, with a subsequent regeneration of the ferric chloride catalyst. CI R-CI + FeCl, R* + FeCl, Ci-Fe-ci R R H - HCI catalyst reganerated Give the reaction mechanism that would produce the 1,4-di-tert-butyl-2,5-dimethoxybenzene, via a Friedel-Crafts alkylation using tert-butyl chloride, ferric chloride and 1,4- dimethoxybenzene.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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