1. The lab mentions using an alternative synthetic route, involving the more traditional Friedel- Crafts method of using an alkyl halide. The Friedel Crafts alkylation, using ferric chloride, proceeds as follows: Firstly, a carbocation is formed from the alkyl halide. Secondly, the alkyl cation reacts with a benzene ring, with a subsequent regeneration of the ferric chloride catalyst. CI R-CI + FeCl, R* + FeCl, Ci-Fe-ci R R H - HCI catalyst reganerated Give the reaction mechanism that would produce the 1,4-di-tert-butyl-2,5-dimethoxybenzene, via a Friedel-Crafts alkylation using tert-butyl chloride, ferric chloride and 1,4- dimethoxybenzene.

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1. The lab mentions using an alternative synthetic route, involving the more traditional Friedel-
Crafts method of using an alkyl halide. The Friedel Crafts alkylation, using ferric chloride,
proceeds as follows:
Firstly, a carbocation is formed from the alkyl halide. Secondly, the alkyl cation reacts with a
benzene ring, with a subsequent regeneration of the ferric chloride catalyst.
CI
R-CI + FeCl,
R* + FeCl,
Ci-Fe-ci
R
R H
- HCI
catalyst reganerated
Give the reaction mechanism that would produce the 1,4-di-tert-butyl-2,5-dimethoxybenzene,
via a Friedel-Crafts alkylation using tert-butyl chloride, ferric chloride and 1,4-
dimethoxybenzene.
Transcribed Image Text:1. The lab mentions using an alternative synthetic route, involving the more traditional Friedel- Crafts method of using an alkyl halide. The Friedel Crafts alkylation, using ferric chloride, proceeds as follows: Firstly, a carbocation is formed from the alkyl halide. Secondly, the alkyl cation reacts with a benzene ring, with a subsequent regeneration of the ferric chloride catalyst. CI R-CI + FeCl, R* + FeCl, Ci-Fe-ci R R H - HCI catalyst reganerated Give the reaction mechanism that would produce the 1,4-di-tert-butyl-2,5-dimethoxybenzene, via a Friedel-Crafts alkylation using tert-butyl chloride, ferric chloride and 1,4- dimethoxybenzene.
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