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1. Shown below are figures of the closed and open structures of the voltage gated potassium channel protein in the cell membrane of a neuronal cell. Extracellular CLOSED Extracellular OPEN Cytosol Region A Cytosol Region A Region A of the channel protein functions as a paddle. The paddles move up and down, opening and closing the central pore through which potassium ions flow. The resting membrane potential of a neuronal cell is -70mV. Action potential +40 a. The action potential graph is shown on the right, at what point in the graph or when would voltage gated potassium channels be closed and when would they be open? Choose from Resting, depolarization, repolarization or refractory period. Describe briefly. Threshold Failed initiations -55 Resting state -70 Stimulus 1 Refractory period b. Would potassium ions move in or out of the cell when the voltage gated potassium channels are open? 1 Time (ms) What kind/type of amino acids would be present in region A of the voltage gated potassium channel protein and how would these amino acids (acidic/basic/nonpolar) help in "voltage- sensing" of the voltage gated potassium channel protein during an action potential? Explain briefly why the region A or paddles move to result in the closing and opening of the pore of the channel protein during the action potential. С. Voltage (mV) Depolarization Repolarization

1. Shown below are figures of the closed and open structures of the voltage gated potassium channel protein in the cell membrane of a neuronal cell. Extracellular CLOSED Extracellular OPEN Cytosol Region A Cytosol Region A Region A of the channel protein functions as a paddle. The paddles move up and down, opening and closing the central pore through which potassium ions flow. The resting membrane potential of a neuronal cell is -70mV. Action potential +40 a. The action potential graph is shown on the right, at what point in the graph or when would voltage gated potassium channels be closed and when would they be open? Choose from Resting, depolarization, repolarization or refractory period. Describe briefly. Threshold Failed initiations -55 Resting state -70 Stimulus 1 Refractory period b. Would potassium ions move in or out of the cell when the voltage gated potassium channels are open? 1 Time (ms) What kind/type of amino acids would be present in region A of the voltage gated potassium channel protein and how would these amino acids (acidic/basic/nonpolar) help in "voltage- sensing" of the voltage gated potassium channel protein during an action potential? Explain briefly why the region A or paddles move to result in the closing and opening of the pore of the channel protein during the action potential. С. Voltage (mV) Depolarization Repolarization

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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1. Shown below are figures of the closed and open structures of the voltage gated potassium channel protein in the cell membrane of a neuronal cell. Extracellular CLOSED Extracellular OPEN Cytosol Region A Cytosol Region A Region A of the channel protein functions as a paddle. The paddles move up and down, opening and closing the central pore through which potassium ions flow. The resting membrane potential of a neuronal cell is -70mV. Action potential +40 a. The action potential graph is shown on the right, at what point in the graph or when would voltage gated potassium channels be closed and when would they be open? Choose from Resting, depolarization, repolarization or refractory period. Describe briefly. Threshold -55 Failed initiations Resting state -70 Stimulus 1 Refractory period b. Would potassium ions move in or out of the cell when the voltage gated potassium channels are open? 1 Time (ms) What kind/type of amino acids would be present in region A of the voltage gated potassium channel protein and how would these amino acids (acidic/basic/nonpolar) help in "voltage- sensing" of the voltage gated potassium channel protein during an action potential? Explain briefly why the region A or paddles move to result in the closing and opening of the pore of the channel protein during the action potential. С. Voltage (mV) Depolarization Repolarization
Transcribed Image Text:1. Shown below are figures of the closed and open structures of the voltage gated potassium channel protein in the cell membrane of a neuronal cell. Extracellular CLOSED Extracellular OPEN Cytosol Region A Cytosol Region A Region A of the channel protein functions as a paddle. The paddles move up and down, opening and closing the central pore through which potassium ions flow. The resting membrane potential of a neuronal cell is -70mV. Action potential +40 a. The action potential graph is shown on the right, at what point in the graph or when would voltage gated potassium channels be closed and when would they be open? Choose from Resting, depolarization, repolarization or refractory period. Describe briefly. Threshold -55 Failed initiations Resting state -70 Stimulus 1 Refractory period b. Would potassium ions move in or out of the cell when the voltage gated potassium channels are open? 1 Time (ms) What kind/type of amino acids would be present in region A of the voltage gated potassium channel protein and how would these amino acids (acidic/basic/nonpolar) help in "voltage- sensing" of the voltage gated potassium channel protein during an action potential? Explain briefly why the region A or paddles move to result in the closing and opening of the pore of the channel protein during the action potential. С. Voltage (mV) Depolarization Repolarization
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