1. NaOH 2. НаС. CH3 NH CI OMe ? 3. NaOH, д

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Predict the major organic product for the following reaction sequence. Be sure your answer accounts for stereochemistry and regiochemistry, where appropriate.

The image depicts a chemical reaction mechanism involving a three-step process. The starting material is a phthalimide, which has a benzene ring fused to a five-membered ring containing two carbonyl groups (C=O) and an NH group.

### Reaction Steps:

1. **First Step:**
   - Reagent: NaOH (sodium hydroxide)
   - This step likely involves the deprotonation of phthalimide by NaOH to form a phthalimide anion.

2. **Second Step:**
   - Reagent: A chiral alkyl halide with the structure \[(CH_3)(CH)(Cl)CH_2CH(OMe)(CH_3)\].
   - Description: This compound has two stereocenters, indicated by the wedges. It includes a chlorine (Cl) and a methoxy group (OMe) on the carbon chain.
   - Likely Reaction: The phthalimide anion could perform a nucleophilic substitution on the alkyl halide.

3. **Third Step:**
   - Reagents: NaOH, heat (\(\Delta\))
   - Likely Reaction: This step might involve further reaction under basic conditions and heat, possibly leading to hydrolysis or rearrangement.

### Question Mark:

The reaction arrow leads to a question mark, indicating that the product of this multi-step process is either unknown or left for deduction or prediction. The overall transformation likely involves a substitution reaction followed by base-catalyzed hydrolysis or another reaction facilitated by heating.

This schematic serves as an educational tool to understand the application of nucleophilic substitution and base-induced reactions in organic chemistry.
Transcribed Image Text:The image depicts a chemical reaction mechanism involving a three-step process. The starting material is a phthalimide, which has a benzene ring fused to a five-membered ring containing two carbonyl groups (C=O) and an NH group. ### Reaction Steps: 1. **First Step:** - Reagent: NaOH (sodium hydroxide) - This step likely involves the deprotonation of phthalimide by NaOH to form a phthalimide anion. 2. **Second Step:** - Reagent: A chiral alkyl halide with the structure \[(CH_3)(CH)(Cl)CH_2CH(OMe)(CH_3)\]. - Description: This compound has two stereocenters, indicated by the wedges. It includes a chlorine (Cl) and a methoxy group (OMe) on the carbon chain. - Likely Reaction: The phthalimide anion could perform a nucleophilic substitution on the alkyl halide. 3. **Third Step:** - Reagents: NaOH, heat (\(\Delta\)) - Likely Reaction: This step might involve further reaction under basic conditions and heat, possibly leading to hydrolysis or rearrangement. ### Question Mark: The reaction arrow leads to a question mark, indicating that the product of this multi-step process is either unknown or left for deduction or prediction. The overall transformation likely involves a substitution reaction followed by base-catalyzed hydrolysis or another reaction facilitated by heating. This schematic serves as an educational tool to understand the application of nucleophilic substitution and base-induced reactions in organic chemistry.
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