Name:Date: 11 9J1 Block 1Benchmark Quarter 3 Study guideTrait: NeurofibromatosisForms of the trait:A The dominant form is neurofibmmatosis, caused by the production of an abnormal form of the proteinneurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-canceroustumors that can interfere with the nervous system and cause blindness Some tumors can convert to acancerous formA The recessive form is a pormal protein-in other words, no neurofibromatosisA typical pedigree for a famity that caries neurofibromatosis is shown below Note that carriers are notindicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosisallele, and the letter "n" for the normal allele.Nnnn3nn1. Is this autosomal or sex-linked? Why?2. Is individual #1 most likely homozygous dominant or heterozygous? Explain how youcan tell3. What is the genotype of individual # 3?4. Can you be sure of the genotype of the affected siblings of the individual #3? Explan

The given information:N= dominant allele causing neurofibromatosisn = recessive allele that…

1. Is this autosomal or sex-linked? Why? 2. Is individual #1 most likely homozygous dominant or heterozygous? Explain how you can tell 3. What is the genotype of individual #3? 4. Can you be sure of the genotype of the affected siblings of the individual # 3? Explan

1. Is this autosomal or sex-linked? Why? 2. Is individual #1 most likely homozygous dominant or heterozygous? Explain how you can tell 3. What is the genotype of individual #3? 4. Can you be sure of the genotype of the affected siblings of the individual # 3? Explan

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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2) Discuss the genetic variability introduced by crossing-over and independent assortment. How is this important in sexually reproducing populations? Would these be important in a single-celled organism that reproduces asexually by mitosis?
. The following pedigree is for a dominant phenotype governed by an autosomal allele. What does this pedigreesuggest about the phenotype, and what can you deduceabout the genotype of individual A?
F. 9. If a man who is heterozygous marries a woman who is homozygous recessive, what would you predict for the genotypes and phenotypes of their children? Can a man and a woman who both suffer from hypercholesterolemia have children who do not have the disease? Explain your answer. Can a man and a woman have children with hypercholesterolemia if neither of them has the disease. Explain your answer. Hr homorgo
9. A true-breeding blue-flower, wrinkled-seed, short-stem, yellow-leaf plant was crossed with a true-breeding red-flower, round- seed, long-stem, green-leaf plant and all of the progeny had the following phenotype: purple-flower, round seed, short-stem, approximately half of the leaves on the plants were yellow and the other half green. Assuming a single gene controls each trait, describe the inheritance pattern for each gene. Inheritance Pattern a. Gene Flower color Seed shape Stem length Leaf color
7) In cats, the gene for coat color is both X-linked and incompletely dominant. There are black coat and yellow coat alleles, with calico (tortoise shell) as the heterozygous form. If a yellow male mates with a calico female, what are the expected offspring phenotypes (in percent)? hbit
1. The figure below shows a pedigree examining the presence of a genetic disorder across multiple generations of a family. Based off this figure, answer the following questions prompted: || IV 3 9 10 5 2 C 6 11 T 7 12 8 15 13 16 14 17 d) What is the genotype for individual #4 in this family pedigree? ||| c) Why are no family members identified as a carrier of this genetic disorder? Figure Key a) Using the figure key provided, identify which members of this family are affected by this genetic disorder in each generation. (Be sure to include sex and generation number for each individual identified). b) Is this an autosomal recessive, autosomal dominant, or sex-linked genetic disorder? Explain. Unaffected Female Unaffected Male Affected Female ||| Affected Male Female Carrier Male Carrier
5. The pedigree below traces the inheritance of Albinism, a genetic disorder. Affected individuals, indicated here by the coloured circles and squares, are unable to make a normal amount of melanin, the chemical that is responsible for eye, skin, and hair colour. Does Albinism appear to be caused by a dominant allele or by a recessive allele? Fill in the genotypes of the individuals whose genotypes can be deduced. What genotypes are possible for each of the other individuals? Explain! Naruto Hinata Reiner Asta Hange Mikasa Eren Historia Luffy Nezuko Zenitsu Tanjiro Son Goku
II. Given the following pedigree below, use Punnett squares for each of the following possibilities: a) Autosomal recessive and b) Autosomal dominant in order to determine what is the mode of transmission of this trait. Disease allele = a or A, depending on mode of transmission of the disease respectively. Your Punnett squares should reflect what you see in generation II. Circle the mode of transmission. Note: Observe the whole pedigree. I Circle the mode of transmission 1 III 6 genotype (circle one): AA Created by Dr. Susan A. Holechek for BIO 340 (2023) 2 1 2 3 4 a) Autosomal recessive 11 x 12 9 XªXa 2 3 5 6 Ở хаха *4 7 b) Autosomal dominant 11x12 8 Aa *Unaffected/No carrier-Normal AaAa
6. There are two enzymes LDH1 and LDH2. The gene that encodes this enzyme is X-linked. You extract the enzyme from different cells in several people and carry out electrophoresis. Give the genotypes for each person Draw the banding pattern that you would expect in the gel. Male with Male with Female Female Heterozygous LDH1 gene homozygous female LDH2 homozygous for LDH2 for LDH1
based on fig 1. Is this karyotype a male or female? Is there a chromosomal disorder? What type of chromosomal disorder?
5. If individual IV-9 is a male, what is the probability that he would be affected with dark blue skin color?