1. Determine if the molecules are chiral (meaning they have chiral centers and lack of plane of symmetry) in the following molecules. For molecules in Newman projections or chairs, it might be helpful to draw the sawhorse or perspective drawing first. NH2 H. CH3 a. b. H3C. C. H3C H CH3 OH NH2 d. e. f. H
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- What size combinatorial library could be constructed using the substituents and diversity sites in these molecules? NH2 NH2 A. 625 B. 125 OH CI C. 256 D. 1024 OH CI1. How many chiral (stereocenters) centers are in the following molecules? Recall that a chiral center will have a carbon atom bonded to four different substituents. Please circle the chiral centers. Structure I HO... III. Br !!! СОН Structure II NH2Of the molecules shown below, how many are chiral? CH3 CH3 CH3 Br Br CH3 CH3 CH3 1 3 4 ..|| ...||
- What are the Chiral centers' absolute configurations (R or S) for the following molecule. Hint (Number 2 is next to CO2H) A. 2S, 3R B. 2R, 3R C. 2S, 3S D.2R, 3S O A OB O C E. One of carbons is not chiral OD HO₂C H OE F H H3C CH₂CH3 B Il Proctorio is sharing your screen. ho Stop sharing HideHi, I am hoving trouble with this question.Which of the following molecule(s) is/are chiral? O O H3C H₂N H₂N Br Zum…... )......… CH3 H C=C=C H CH3 CO₂H CO₂H Br H CH3 CH3
- 4. Given the following Newman projection, assign the absolute configuration (R,S) at the one stereocenter. (Hint: You may want to redraw the projection in another way.) CH2 CH2 CH3 Но CH3 Give the stereochemical relationship between each pair of isomers. Examples are same compounda.) 0 b.) 1 c.) 2 d.) 3 e.)4Which of the following compounds are chiral? H CI H I. only I. O II. only I. and III. II. and III. CI Ette II. III.