1. CO2 1. LAH acetoyl chloride Mg(s) Et,0 NaOH PBr3 Jones 2.H3O* 2. Hао AICI3 HO.

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What reagents are required to carry out the following part of the above synthesis?

**Transcription for Educational Website:**

---

The image presents a chemical reaction scheme illustrating the synthesis of a target compound. 

**Chemical Reagents and Steps:**

1. **LAH (Lithium Aluminium Hydride)** and **H2O** are noted in the first reaction box. This suggests a reduction process, possibly converting an ester or a carbonyl group to an alcohol.

2. **NaOH** is indicated in the second reaction box, typically used for neutralization or as a base in reactions such as aldol condensation.

3. **Acetyl Chloride** and **AlCl3** are listed, suggesting a Friedel-Crafts acylation. This is typically used to introduce an acyl group into an aromatic ring.

4. **PBr3 (Phosphorus tribromide)** is shown in the next box, which is typically used for converting alcohols to alkyl bromides.

5. **Jones Reagent** is present, which is commonly used for oxidizing primary and secondary alcohols to carboxylic acids or ketones.

6. **Mg(s) and Et2O (Diethyl Ether)** are indicated, typically used in Grignard reactions for creating carbon-carbon bonds.

7. The final set includes **CO2** and **H3O+**, indicating a carboxylation process likely followed by acid workup.

**Chemical Structure Diagram:**

- The diagram shows the transformation of a ketone starting material, with a branched chain, into the final product which contains an aromatic ring and a carboxylic acid group.
- Each reaction step is linked with arrows showing the sequence of transformations with intermediate compounds being formed throughout the synthesis.

This schematic provides an overview of the synthetic route, highlighting the key reagents and the structural changes in the molecular framework leading to the desired final compound.
Transcribed Image Text:**Transcription for Educational Website:** --- The image presents a chemical reaction scheme illustrating the synthesis of a target compound. **Chemical Reagents and Steps:** 1. **LAH (Lithium Aluminium Hydride)** and **H2O** are noted in the first reaction box. This suggests a reduction process, possibly converting an ester or a carbonyl group to an alcohol. 2. **NaOH** is indicated in the second reaction box, typically used for neutralization or as a base in reactions such as aldol condensation. 3. **Acetyl Chloride** and **AlCl3** are listed, suggesting a Friedel-Crafts acylation. This is typically used to introduce an acyl group into an aromatic ring. 4. **PBr3 (Phosphorus tribromide)** is shown in the next box, which is typically used for converting alcohols to alkyl bromides. 5. **Jones Reagent** is present, which is commonly used for oxidizing primary and secondary alcohols to carboxylic acids or ketones. 6. **Mg(s) and Et2O (Diethyl Ether)** are indicated, typically used in Grignard reactions for creating carbon-carbon bonds. 7. The final set includes **CO2** and **H3O+**, indicating a carboxylation process likely followed by acid workup. **Chemical Structure Diagram:** - The diagram shows the transformation of a ketone starting material, with a branched chain, into the final product which contains an aromatic ring and a carboxylic acid group. - Each reaction step is linked with arrows showing the sequence of transformations with intermediate compounds being formed throughout the synthesis. This schematic provides an overview of the synthetic route, highlighting the key reagents and the structural changes in the molecular framework leading to the desired final compound.
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