There are 4 major steps to complete the following synthesis. Match the steps with appropriate reagents/conditions. Br Step #1 Step #2 Step #3 Step #4
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
![**Title: Organic Synthesis Steps and Reagents**
**Description:**
This educational module helps students understand a four-step synthesis process. The objective is to match each step with its corresponding reagents or conditions.
**Diagram Explanation:**
The image features a chemical structure transformation from a bromoalkane on the left to a keto-amide on the right. This transformation consists of four major steps labeled as Step #1, Step #2, Step #3, and Step #4.
**Dropdown for Each Step:**
- **Step #1 Selection:**
- [Dropdown: Mg/THF]
- **Step #2 Selection:**
- [Dropdown: 1. CO2 2. H3O+]
- **Options for Step #3 (Displayed in a dropdown menu):**
- 1. LiAlH4 2. H3O+
- MeNH2
- 1. CO2 2. H3O+
- SOCl2
- NaCN
- H3O+/heat
- Mg/THF
Students are required to choose the appropriate reagent/condition for Step #3 from the provided list.
**Instructions:**
- Match each synthesis step with the appropriate reagents/conditions from the dropdown menus.
- Consider the chemical transformations needed at each stage to successfully move from the reactant to the desired product.
This activity enhances understanding of reagent function and reaction mechanisms in organic synthesis.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Ffe60b8ca-eedf-45d0-98d7-6f8efd9e6473%2F2f693a3e-7ae7-4e60-b34e-87d8f5235e25%2Fmcmoo3_processed.jpeg&w=3840&q=75)
Step by step
Solved in 3 steps with 1 images
