1 2 3456 1-Control with no virus nucleic acid 2-Virus nucleic acid no treatment 3-Virus nucleic acid digested with Enzyme A 4-Virus nucleic acid digested with Enzyme B 5-Virus nucleic acid digested with Enzyme C 6-Virus nucleic acid base hydrolysis
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You have isolated a new virus that you want to classify using the Baltimore approach to classification. However, you don’t have much to work with. Just an agarose gel, ethidium bromide to strain the
From these results, what type of genome do you think the virus has? Briefly explain your answer.
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- All of the following statements correctly describes the properties of Influenza A virus EXCEPT A-Viral transcription occurs in the nucleus B-Mature virion are released by budding C-Single stranded positive sense RNA virus D-Attaches to cell-surface sialic acidArrange the following list into the correct sequence for part of the cycle of a retrovirus: 1. dsDNA integrated into host DNA 2.viral proteins synthesized on host ribosomes 3. viral DNA uses host enzymes to transcribe viral RNA 4. reverse transcriptase catalyzes synthesis of ssDNA 5. synthesis of second DNA strand (a) 5, 2, 1, 3, 4 (b) 5, 2, 3, 4, 1 (c) 4, 5, 1, 3, 2 (d) 4, 1, 2, 3, 5 (e) 2, 1, 3, 4, 5Discuss the following statement: “Viruses exist in the twilight zone of life: outside cells they are simply dead assemblies of molecules; inside cells, however, they are alive.”
- 3. The table on the last page compares for each of four different proteolytic enzymes the chemical bonding structure of a classical substrate with the structures of two competitive inhibitors. For each substrate structure an arrow indicates the position of the scissile bond, i.e., the bond that is cleaved through catalytic action. For each enzyme, one of the inhibitors is a classical competitive inhibitor while the other is a transition-state inhibitor analog. While ordinary competitive inhibitors are associated with (dissociation) inhibitor equilibrium con- stants of ~10-3 to 10-6 M, transition-state analogs exhibit inhibitor constants ≤ 10-⁹ M. (a) For each enzyme draw a circle around those parts of the substrate that account for specificity of substrate recognition. (b) For each enzyme identify the transition-state inhibitor analog by drawing a circle around it and give a brief explanation of why it mimics the structure of the transition-state species. (c) Draw a "generic"…The relative amounts of each nitrogenous base are tabulated here for four different viruses. For each virus listed in the following table, indicate whether its genetic material is DNA or RNA and whether it is single stranded or double stranded. Explain your reasoning. Virus т G A 12 12 II 23 16 16 23 III 34 42 18 39 IV 24 35 27 17The relative amounts of each nitrogenous base are tabulated here for four different viruses. For each virus listed in the following table, indicate whether its genetic material is DNA or RNA and whether it is single stranded or double stranded. Explain your reasoning. Virus T C U G A I 0 12 9 12 9 II 23 16 0 16 23 III 34 42 0 18 39 IV 0 24 35 27 17
- produce a diagram of the replication of a viral genome of stranded RNA simple [+] and mRNA production via Reverse Transcriptase. Produce a diagram of the replication and early maturation of a virus wrapped Produce a diagram of the replication and early maturation of a virus naked. Produce a diagram of the release of an enveloped virus by budding.A (+) Sense virus makes a negative sense copy of its genome. Part of the (+) Sense genome has the sequence: 3'-GUGGCAGUA-5'. What is the sequence of the (-) sense copy? O 5'-AUGACGGUG-3' O 5' - CACCGUCAU - 3' O 3'-AUGACGGUG-5' O 5' - UACUGCCAC - 3'Can Cytomegalovirus (CMV) release any toxicant? What I mean is if the virus perform any kind of chemical rection while inactive like when it is in the environment releasing toxins or when is active inside the host such as inside the human body?
- 27. Class VI animal viruses include HIV, Based on the type of viral genome, how is this class distinguished from the other classes of animal virus? A) It has double stranded RNA. B) It has single stranded RNA that serves as mRNA (positive sense). C) It has single stranded RNA that serves as a template for the synthesis of DNA. D) It has single stranded RNA that serves as a template for mRNA (anti-sense). does HIVWhich of the following highly contagious viruses is a single-stranded ribonucleic acid (RNA) virus with a helical capsid and envelope and is transmitted by coming in contact with respiratory secretions? "This is a highly contagious respiratory illness transmitted when an infected person coughs or sneezes virus particles into the air," the health department said in a written statement. "It's so contagious that if one person is sick and spreading measles, nine out of 10 people around them who aren't immune will get it, too." Group of answer choices a. Measles b. Parvovirus c. Coxsackie virus A d. RhinovirusWhich type of virus must contain an RNA replicase packaged in the viral particle in order to carry out its replicative cycle? A (+) ssRNA virus O A dsDNA virus A (+) ssDNA virus OA (-) ssRNA virus