HW1

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Health Science

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Dec 6, 2023

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CHLH 573 - Homework Assignment 1 1. (15 pts) Determine whether each of the following variables is a categorical or quantitative variable. If the variable is quantitative variable, determine whether it is a discrete or continuous variable. If the variable is a categorical variable determine whether it is a nominal or an ordinal variable. Answer 1: (a) Cancer stage (I,II and III) – Categorical-Ordinal (b) Percent body fat – Quantitative-Continuous (c) Hair color – Categorical-Nominal (d) Number of new COVID-19 cases in IL on 08/01/2020 – Quantitative-Discrete 2. (30 pts) Suppose a nutritionist is studying the caloric content of a new low-fat ice-cream that is under development. A random sample of 11 observations yields the following data on caloric content of this ice-cream. Observation Caloric content Observation Caloric content Observation Caloric content 1 127 5 126 9 125 2 129 6 134 10 131 3 130 7 127 11 135 4 116 8 117 (a) Using the data given in Table 1, estimate the sample (1) mean, (2) mode, (3) standard deviation, (4) range, and (5) interquartile range (15 pts). Answer:
(b) Based on the IQR you calculated above, find outliers in the dataset if there is any (5 pts). Answer: (c) Draw the boxplot of caloric content by hand (10 pts) Answer:
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3. (30 pts) Some studies of Alzheimer’s disease (AD) have shown an increase in CO2 production in patients with the disease. In one such study the following CO2 values were obtained from 16 neocortical biopsy samples from AD patients. 1009 1280 1180 1255 1547 2352 1956 1080 1776 1767 1680 2050 1452 2857 3100 1621 Assume the population of such values is normally distributed. Answer the following questions: (a) Suppose population standard deviation is 350. Provide 95% Z-statistics confidence interval for mean level of CO2. (10 pts) Answer: (b) Now suppose we do not know the standard deviation on the population level. Provide 95% confidence interval for mean level of CO2. (10pts) Answer: (c) Compare the intervals in (a) and (b). Which one is wider? Why? (10 pts) Answer: Confidence interval is wider for t-statistics compared to z-statistics, because sample standard deviation (used for t-statistics) is larger than population standard deviation(used in z- statistics). Hint : You will need Stata to calculate the critical values in answering (b) and (c). Please directly copy and paste the Stata commends. No need to put them in the do file to submit.
4. [Stata] (25 pts) Data from a hypothetical sample of 32 white males over 40 years of age taken from the text Applied Regression Analysis by Kleinbaum, et al. (a) Read sbp.csv into Stata. Summarize systolic blood pressure for all observations. What is the 25%, 50% and 75% (5 pts)? Answer: (Stata commend: summarize sbp, detail) sbp PercentilesSmallest 1% 120 120 5% 122 122 10% 129 126 Obs 32 25% 134.5 129 Sum of wgt. 32 50% 143 Mean 144.5313 LargestStd. dev. 14.39755 75% 152 164 90% 164 166 Variance 207.2893 95% 170 170 Skewness .5020894 99% 180 180 Kurtosis 2.72561 Here, 25% is 134.5 50% is 143 75% is 152 (b) Summarize systolic blood pressure by smoking status. What is the 25%, 50% and 75% of systolic blood pressure for non-smoker and current or former smoker respectively? Do a side-by-side boxplot of systolic blood pressure between two smoking groups. (15 pts) Answer: (Stata commend: by smk, sort:sum sbp,detail) -> smk = 0 (non-smokers) sbp Percentiles Smallest 1% 120 120 5% 120 122
10% 122 130 Obs 15 25% 132 132 Sum of wgt. 15 50% 138 Mean 140.8 LargestStd. dev. 12.90183 75% 152 152 90% 161 152 Variance 166.4571 95% 164 161 Skewness .2029599 99% 164 164 Kurtosis 2.277845 -> smk = 1 (smokers) sbp PercentilesSmallest 1% 126 126 5% 126 129 10% 129 132 Obs 17 25% 138 134 Sum of wgt. 17 50% 145 Mean 147.8235 LargestStd. dev. 15.21198 75% 160 162 90% 170 166 Variance 231.4044 95% 180 170 Skewness .5401733 99% 180 180 Kurtosis 2.419973 systolic blood pressure for non-smoker: 25% is 132 50% is 138 75% is 152 systolic blood pressure for current/former-smoker: 25% is 138 50% is 145 75% is 160
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Boxplot: [stata commend: graph box sbp, over(smk)] (c) What can you conclude (5pts)? Answer: From the observations we can conclude that Non-smokers have lower systolic blood pressure than current/past smokers, therefore they are at lesser risk of developing hypertension. This proves direct relationship between smoking and risk of developing hypertension. Variables: systolic blood pressure (SBP), body size (QUET=100(weight/height2)), age (AGE) and smoking history (SMK=0 if non-smoker, SMK=1 if current or former smoker). (You need to record all commends used for this question in the do file and submit it.)