chp23 urogenital infections worksheet-1

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BIO208, Lecture #25 Genitourinary Infections, Chapter 23 Which of the following represent the protective characteristics of urine. Check all that apply. Acidic pH Contains mucus Contains lysozyme which breaks down peptidoglycan Contains lactoferrin, an iron-binding protein Contains secrectory IgA Fill in the blanks The urogenital system is really two distinct organ systems; the urinary system and the reproductive system. Within the urinary system, urine keeps most areas sterile; the outer region of the urethra however, harbors normal biota such as strepcocci, staphylococci, and lactobacilli. In females the shortness of this structure allows for easy entry of GI tract microbes into the bladder, which often results in urinary tract infections. In males , the normal biota of the genital tract is nearly identical to species colonizing external portions of the penis. Word bank: males females mucus urine reproductive semen urine flow urethra urogenital Case study: In April 1990, the El Paso County (Colorado) Health Department recognized an outbreak of drug- resistant gonorrhea in Colorado Springs. 56 cases of penicillin-resistant Neisseria gonorrheae occurred from December 1989 through March 1991. To gather information about the outbreak, people were interviewed at STD clinics, in their homes, and at locations where they congregate. The network analysis included 410 persons related through a densely connected set of social or sexual associations. This network included adolescents and young adults associated with street gangs and drug use. 200 persons with infections names 558 sex partners in the socio-sexual network. 1. Besides Neisseria gonorrheae , what other diseases are the individuals in this socio-sexual network at risk for acquiring? A) Influenza B) Impetigo C) Chlamydia D) MRSA E) Tuberculosis 1
2. What cell structure enables Neisseria gonorrheae to attach to the urethra and avoid being washed away? A) LPS B) Ability to survive in the phagocyte C) Fimbraea D) M protein E) Capsule 3. How would you treat those that have been infected with drug-resistant gonorrhea? A) Topical (apply to the skin) antibiotic cream B) Handwashing C) Vaccination D) Condoms E) Oral antibiotic 4. How can this disease be prevented? A) Condoms B) Vaccination C) Prophylactic (preventative) antibiotic treatment D) Proper hygiene E) Abstinence or condoms 5. How would you propose to stop the outbreak described? I would propose that you treat the area with an antibiotic other than penicillin. I would also recommend educating people about safe sex practices- condoms and transmission- sex. 6. Why can’t physicians simply increase the concentration of penicillins to overcome the infection? The microbe is resistant to penicillin, and a higher concentration won’t change that. Select the statements that correctly compare and contrast infections by Neisseria gonorrheae and Chlamydia trachomatis . C. trachomatis is an obligate intracellular parasite whereas N. gonorrheae proliferates outside of a host cell. Antibiotic resistance is a major threat in strains of C. trachomatis . Antibiotics can be used to treat non-resistant cases of gonorrhea and chlamydia. Overall, chlamydia is more prevalent but both diseases predominantly affect the 20-24 year-old age group. Individuals presenting with typical discharge symptoms are assumed to have a co-infection and are treated for both chlamydia and gonorrhea. A vaccination is available for both chlamydia and gonorrhea and as a result, the incidence of both is decreasing. 2
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