Cell Signaling Assignment 2

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Arizona State University *

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181

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Biology

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Apr 3, 2024

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9

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3/23/24, 10:07 PM Cell Signaling Assignment 2: BIO 181: General Biology I (2024 Spring) https://canvas.asu.edu/courses/170670/quizzes/1282737?module_item_id=12175067 1/9 Cell Signaling Assignment 2 Due Mar 4 at 11:59pm Points 13 Questions 10 Available Feb 26 at 2:50pm - Mar 5 at 11:59pm Time Limit None Allowed Attempts 2 This quiz was locked Mar 5 at 11:59pm. Attempt History Attempt Time Score KEPT Attempt 2 24 minutes 10 out of 13 LATEST Attempt 2 24 minutes 10 out of 13 Attempt 1 44 minutes 10 out of 13 Score for this attempt: 10 out of 13 Submitted Mar 4 at 10:29pm This attempt took 24 minutes. Question 1 1 / 1 pts In the 14th century, the bubonic plague killed more than 2/3 of Europeans. The plague was transmitted by fleas who were infected by rats and would inject a bacteria into the bloodstream that shuts down a person's immune system. While not as common today, the bubonic plague still exists, infecting around a thousand people a year. There are about seven cases in the United States each year, many of those in Arizona and New Mexico. Scientists have discovered that the bacteria works by affecting signaling pathways in the immune system.
3/23/24, 10:07 PM Cell Signaling Assignment 2: BIO 181: General Biology I (2024 Spring) https://canvas.asu.edu/courses/170670/quizzes/1282737?module_item_id=12175067 2/9 Correct! It is hydrophilic. It is hydrophobic. Question 2 1 / 1 pts Correct! It is polar. It is nonpolar. Question 3 1 / 1 pts Correct! response termination The bacteria uses a needle-like structure to create a physical pathway through the plasma membrane so the signaling molecule can enter the host cell's cytoplasm. This tells us what about the signaling molecule the bacteria releases? In the 14th century, the bubonic plague killed more than 2/3 of Europeans. The plague was transmitted by fleas who were infected by rats and would inject a bacteria into the bloodstream that shuts down a person's immune system. While not as common today, the bubonic plague still exists, infecting around a thousand people a year. There are about seven cases in the United States each year, many of those in Arizona and New Mexico. Scientists have discovered that the bacteria works by affecting signaling pathways in the immune system. The bacteria uses a needle-like structure to create a physical pathway through the plasma membrane so the signaling molecule can enter the host cell's cytoplasm. This tells us what about the signaling molecule the bacteria releases? In the 14th century, the bubonic plague killed more than 2/3 of Europeans. The plague was transmitted by fleas who were infected by rats and would inject a bacteria into the bloodstream that shuts down a person's immune system. While not as common today, the bubonic plague still exists, infecting around a thousand people a year. There are about seven cases in the United States each year, many of those in Arizona and New Mexico. Scientists have discovered that the bacteria works by affecting signaling pathways in the immune system. Scientists discovered that the bacteria causes a reduced response of the immune system. Based on this information, which part of the cell signaling pathway would you predict is being affected?
3/23/24, 10:07 PM Cell Signaling Assignment 2: BIO 181: General Biology I (2024 Spring) https://canvas.asu.edu/courses/170670/quizzes/1282737?module_item_id=12175067 3/9 reception transduction Question 4 0 / 1 pts The bacteria is amplifying immune response. The bacteria is not affecting immune response. Correct Answer The bacteria is somehow affecting an immune response. You Answered The bacteria is preventing termination of immune response. Question 5 0 / 1 pts In the 14th century, the bubonic plague killed more than 2/3 of Europeans. The plague was transmitted by fleas who were infected by rats and would inject a bacteria into the bloodstream that shuts down a person's immune system. While not as common today, the bubonic plague still exists, infecting around a thousand people a year. There are about seven cases in the United States each year, many of those in Arizona and New Mexico. Scientists have discovered that the bacteria works by affecting signaling pathways in the immune system. Scientists discovered that the bacteria causes a reduced response of the immune system. Based on this information, what would you predict is happening? In the 14th century, the bubonic plague killed more than 2/3 of Europeans. The plague was transmitted by fleas who were infected by rats and would inject a bacteria into the bloodstream that shuts down a person's immune system. While not as common today, the bubonic plague still exists, infecting around a thousand people a year. There are about seven cases in the United States each year, many of those in Arizona and New Mexico. Scientists have discovered that the bacteria works by affecting signaling pathways in the immune system. Based on what you know so far, which of these pathways do you think is the most likely?
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3/23/24, 10:07 PM Cell Signaling Assignment 2: BIO 181: General Biology I (2024 Spring) https://canvas.asu.edu/courses/170670/quizzes/1282737?module_item_id=12175067 4/9 Correct Answer C A You Answered B Question 6 2 / 2 pts A. B. C. In the 14th century, the bubonic plague killed more than 2/3 of Europeans. The plague was transmitted by fleas who were infected by rats and would inject a bacteria into the bloodstream that shuts down a person's immune system. While not as common today, the bubonic plague still exists, infecting around a thousand people a year. There are about seven cases in the United States each year, many of those in Arizona and New Mexico. Scientists have discovered that the bacteria works by affecting signaling pathways in the immune system.
3/23/24, 10:07 PM Cell Signaling Assignment 2: BIO 181: General Biology I (2024 Spring) https://canvas.asu.edu/courses/170670/quizzes/1282737?module_item_id=12175067 5/9 Bacteria amplify production of interleukin 7. Correct! Bacteria amplify the production of interleukin 10. Bacteria reduce the production of interleukin 1. Bacteria amplify the number of immune cells. Question 7 1 / 1 pts Scientists measure several interleukin factors and also discover that interleukin 10 is responsible for reducing the immune response. Here is what they find: What do you predict is happening? In the 14th century, the bubonic plague killed more than 2/3 of Europeans. The plague was transmitted by fleas who were infected by rats and would inject a bacteria into the bloodstream that shuts down a person's immune system. While not as common today, the bubonic plague still exists, infecting around a thousand people a year. There are about seven cases in the United States each year, many of those in Arizona and New Mexico. Scientists have discovered that the bacteria works by affecting signaling pathways in the immune system. Scientists discover that interleukin 10 is responsible for reducing immune response. Based on the findings above, what would you predict the simplified pathway might look like?
3/23/24, 10:07 PM Cell Signaling Assignment 2: BIO 181: General Biology I (2024 Spring) https://canvas.asu.edu/courses/170670/quizzes/1282737?module_item_id=12175067 6/9 B Correct! C A Question 8 0 / 1 pts A. B. C. In the 14th century, the bubonic plague killed more than 2/3 of Europeans. The plague was transmitted by fleas who were infected by rats and would inject a bacteria into the bloodstream that shuts down a person's immune system. While not as common today, the bubonic plague still exists, infecting around a thousand people a year. There are about seven cases in the United States each year, many of those in Arizona and New Mexico. Scientists have discovered that the bacteria works by affecting signaling pathways in the immune system.
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3/23/24, 10:07 PM Cell Signaling Assignment 2: BIO 181: General Biology I (2024 Spring) https://canvas.asu.edu/courses/170670/quizzes/1282737?module_item_id=12175067 7/9 There is no change. Correct Answer Immune function is restored. Immune function continues to decrease. You Answered Immune function increases. Question 9 2 / 2 pts Scientists discover that interleukin 10 is responsible for reducing immune response, so they block interleukin 10 production in the cells. What would you expect to happen? In the 14th century, the bubonic plague killed more than 2/3 of Europeans. The plague was transmitted by fleas who were infected by rats and would inject a bacteria into the bloodstream that shuts down a person's immune system. While not as common today, the bubonic plague still exists, infecting around a thousand people a year. There are about seven cases in the United States each year, many of those in Arizona and New Mexico. Scientists have discovered that the bacteria works by affecting signaling pathways in the immune system. Scientists discover that interleukin 10 is responsible for reducing immune response, so they block interleukin 10 production in the cells. They expected that immune function would be restored, but it was not. Thus, they measured amount of immune cells being produced in another pathway. This is what they found:
3/23/24, 10:07 PM Cell Signaling Assignment 2: BIO 181: General Biology I (2024 Spring) https://canvas.asu.edu/courses/170670/quizzes/1282737?module_item_id=12175067 8/9 Correct! TNF1 is being suppressed. TNF1 is being amplified. TNF2 is being amplified. TNF3 is being suppressed. Question 10 2 / 2 pts TNF1 decreases immune response. Correct! Based on this, what would you say is happening? In the 14th century, the bubonic plague killed more than 2/3 of Europeans. The plague was transmitted by fleas who were infected by rats and would inject a bacteria into the bloodstream that shuts down a person's immune system. While not as common today, the bubonic plague still exists, infecting around a thousand people a year. There are about seven cases in the United States each year, many of those in Arizona and New Mexico. Scientists have discovered that the bacteria works by affecting signaling pathways in the immune system. Scientists discover that interleukin 10 is responsible for reducing immune response, so they block interleukin 10 production in the cells. They expected that immune function would be restored, but it was not. Based on this graph, what would you predict that TNF1 does?
3/23/24, 10:07 PM Cell Signaling Assignment 2: BIO 181: General Biology I (2024 Spring) https://canvas.asu.edu/courses/170670/quizzes/1282737?module_item_id=12175067 9/9 TNF1 increases immune response. Quiz Score: 10 out of 13
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