Week 7 Lab Document

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Chamberlain University College of Nursing *

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252

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Biology

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Feb 20, 2024

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docx

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Uploaded by LieutenantScience11488

Week 7 Endocrine System Lab Learning Objectives: Understand hormonal feedback mechanisms. Introduction: The body uses a variety of mechanisms to keep hormone levels tightly regulated. A critical mechanism is using feedback loops in which a hormone, such as estrogen, feeds back to control its own production. This can be either a positive or a negative feedback loop. In a negative feedback loop, a stimulus, such as a hormone or a neurotransmitter, causes the release of a product, such as estrogen. When the product reaches a certain level in the bloodstream, it signals to the hypothalamus and anterior pituitary to stops further release of the stimulating hormone or neurotransmitter and thereby leads to reduced levels of the product. A positive feedback loop is the opposite loop. A product signals to produce more of the stimulating hormone or neurotransmitter which causes a continuous increase of the product. Can we control hormones? In this simulation you will learn different hormones’ influence on fertility. We will perform animal friendly virtual experiments on some beautiful bunnies to try to keep the petting zoo population from getting out of control! Assignment: Part 1 Complete the Labster " Endocrinology: Learn how contraceptives work” Have the lab report with you as you go through the lab to record data. The theory section is a helpful resource. Part 2 Complete the lab report. Endocrine System Lab Report 1. What hormones were used in the fertility experiments? (2 points) The hormones used in the experiment were testosterone, progesterone, and GnRH. 2. Data: (2 points; ½ point each) Endometrial thickness (0-6) Control 6 GnRH 4 Progesterone 0 Testosterone 0

3. What is the importance of a having a control in an experiment? (2 points) A control ensures that what is claimed to be tested is what is being tested. It minimizes the effects of other factors besides what is being tested. 4. What effect does an increase in GnRH release from the hypothalamus have on the pituitary? (2 points) GnRH stimulates the pituitary gland to produce Follicle Stimulating Hormone (FSH), which causes oocyte (egg) development and an increase in estrogen levels. 5. a. Which of the hormones tested would likely decrease fertility in females? (2 points) Follicle Stimulating Hormone (FSH) would decrease fertility in females as it is the hormone that causes the development of the oocyte (egg). b. Which of the hormones tested would likely decrease fertility in males? (1 point) Follicle Stimulating Hormone (FSH) would decrease fertility in males as it is the hormone that causes sperm development in males. 6. Why might testosterone not be an ideal contraceptive choice for females? (2 points) Testosterone is not an ideal contraceptive choice in females because too much testosterone may cause a woman to have stronger male features such as a deep voice, excessive body hair, balding, increased muscle mass, decreased breast size and an enlarged clitoris. It can also cause infertility and obesity. 7. Discuss an example of a negative hormonal feedback mechanism other than those involving the reproductive system. (2 points) Regulation of Blood Glucose Levels: 1) Increase in blood glucose level. 2) Pancreas release insulin into the blood. 3) Some glucose is stored in the liver as glycogen, while the rest is taken up by the cells and used for energy. 4) Blood glucose levels decrease. 5) Body is back in homeostasis. Grading Rubric for Lab Report Activity Deliverable Points Part 1 Complete Labster 15 Part 2 Complete lab report 15 Total Complete all lab activities 30

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