19E3AE9C-64C4-41B9-844E-D8756351C5BF

Question 24 Correct Mark 1.00 out of 1.00 " Flag question Several genes code for enzymes that are responsible for histidine biosynthesis in Escherichia coli. Part of the amino acid sequence for one of these enzymes is: AUG CCU UGG GCC CAA AAA UGC A series of mutants that have lost activity for this enzyme are recovered. The mutant products are analyzed and found to have the following amino acid sequences: Mutant 1: Met-Pro-Trp-Pro-Glu-Lys-Cys Mutant 2: Met-Pro Mutant 3: Met-Pro-Cys-Gly-Pro-Lys-Met Mutant 4: Met-Pro-Trp-Pro-Lys-Asp Choose the correct type of mutation that occurred in the DNA to produce each mutant type. Nonsense [ Mutant 2 ¢ }/ Point [ Mutant 1l ¢ ]\/ Addition [ Mutant 3 & ]\/ Deletion [Mutant = j\/ Mutant 1 - Point AUG CCU UGG GCC CAA AAA UGC Ala (GCC) changed to Pro (CCC). G is switched to C. Mutant 2 - Nonsense AUG CCU UGG GCC CAA AAA UGC Trp (UGG) changed to stop codon (UGA) Mutant 3 - Addition AUG CCU UG_G GCC CAA AAA UGC Trp (UGG) is changed to Cys (UG-U/Q) B B e el B N e B N R e N e e eyl e e e e S O e e e e