Chapter FRP, Problem 30P

Interpretation Introduction

Interpretation:

The reagents needed for the given multistep transformation are to be indicated.

Concept introduction:

舧 Electrophiles are electron-deficient species, which has positive or partially positive charge. Lewis acids are electrophiles, which accept electron pair.

舧 Nucleophiles are electron-rich species, which has negative or partially negative charge. Lewis bases are nucleophiles, which donate electron pair.

舧 Substitution reaction: A reaction in which one of the hydrogen atoms of a hydrocarbon or a functional group is substituted by any other functional group is called substitution reaction.

舧 Elimination reaction: A reaction in which two substituent groups are detached and a double bond is formed is called elimination reaction.

舧 Addition reaction: It is the reaction in which unsaturated bonds are converted to saturated molecules by the addition of molecules.

舧 The target molecule can be synthesized by reacting the suitable, commercially-available ketone with the suitable Grignard reagent. The Grignard reagent can be synthesized from the alkyl halide and metallic magnesium in ether. The alkyl halide can be synthesized from the starting material employing the Wohl-Ziegler reaction using 1 equivalent NBS and a radical initiator like benzoyl peroxide.

舧 The retrosynthesis is as follows: