Chapter C, Problem 11P

C.11 Go to the website http $\text{://}$ www $\text{.}$ ncbi $\text{.}$ nlm $\text{.}$ nih $\text{.}$ gov $\text{/}$ omim and enter $\text{“}$ Lynch syndrome $\text{”}$ in the Search box at the top of the page. From the list of options given, select $\text{“\#120435-}$ Lynch Syndrome. $\text{”}$ Use the information you retrieve to answer the following questions.

There are two types of Lynch syndrome, what are they?

What genes are most commonly mutated in Lynch syndrome?

Provide a brief summary of the normal functions of the protein products of these genes.

What are the approximate rates of cancer that develop in people carrying a mutation of one of these genes?