
To analyze:
Enlist three to four important points that should be discussed with a genetic counselor to determine an individual’s risk of cancer.
Introduction:
Cancer is a genetic disease. It’s not a single disease; rather it is two or more hundreds of diseases. It affects almost all organ systems, tissues, and cells. The growth of the cells is uncontrolled, and the cells that lead to cancer are abnormal. There are over two hundred types of known cancers. The causative agents to cause cancer are –chemicals, ionization radiation, pathogens, human genetics, compound exposure, poor lifestyle, diet, environmental factors etc.
It grows proliferate over time with the increase in intrinsic and acquired treatment resistance.

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Chapter C Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
- 1. Match each vocabulary term to its best descriptor A. affinity B. efficacy C. inert D. mimic E. how drugs move through body F. how drugs bind Kd Bmax Agonist Antagonist Pharmacokinetics Pharmacodynamicsarrow_forward50 mg dose of a drug is given orally to a patient. The bioavailability of the drug is 0.2. What is the volume of distribution of the drug if the plasma concentration is 1 mg/L? Be sure to provide units.arrow_forwardDetermine Kd and Bmax from the following Scatchard plot. Make sure to include units.arrow_forward
- Choose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forward
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