Prescott's Microbiology
11th Edition
ISBN: 9781260211887
Author: WILLEY, Sandman, Wood
Publisher: McGraw Hill
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Chapter 9.4, Problem 4CC
Retrieve, Infer, Apply
What are antimetabolites? Why are these effective against protozoan pathogens while the other drugs presented here generally are not?
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2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0
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Chapter 9 Solutions
Prescott's Microbiology
Ch. 9.1 - Prob. 1CCCh. 9.1 - Louis Pasteur is often credited with saying,...Ch. 9.2 - Prob. 1CCCh. 9.2 - Prob. 2CCCh. 9.2 - Prob. 3CCCh. 9.3 - To which antibiotic (A, B, C, D, or E) is the...Ch. 9.3 - Prob. 1CCCh. 9.3 - Prob. 2CCCh. 9.3 - Prob. 3CCCh. 9.4 - MICRO INQUIRY What is the difference between...
Ch. 9.4 - Prob. 2MICh. 9.4 - Prob. 3MICh. 9.4 - MICRO INQUIRY How is the mechanism by which...Ch. 9.4 - Prob. 5MICh. 9.4 - Prob. 1CCCh. 9.4 - Prob. 2CCCh. 9.4 - Prob. 3CCCh. 9.4 - Retrieve, Infer, Apply What are antimetabolites?...Ch. 9.5 - Prob. 1CCCh. 9.5 - Prob. 3CCCh. 9.5 - Prob. 4CCCh. 9.6 - Prob. 1CCCh. 9.6 - Prob. 2CCCh. 9.6 - Prob. 3CCCh. 9.7 - MICRO INQUIRY What is the mechanism by which...Ch. 9.7 - Prob. 1CCCh. 9.7 - Retrieve, Infer, Apply Why is malaria, like...Ch. 9.7 - Prob. 3CCCh. 9.8 - Prob. 1CCCh. 9.8 - Prob. 2CCCh. 9.8 - Prob. 3CCCh. 9.8 - Prob. 4CCCh. 9 - Prob. 1RCCh. 9 - Prob. 2RCCh. 9 - Prob. 1ALCh. 9 - Prob. 2ALCh. 9 - Prob. 3ALCh. 9 - Prob. 4ALCh. 9 - Prob. 5AL
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