HUMAN BIOLOGY (LOOSELEAF)
HUMAN BIOLOGY (LOOSELEAF)
16th Edition
ISBN: 9781260482690
Author: Mader
Publisher: MCG
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Chapter 9.4, Problem 3CYP
Summary Introduction

To review:

The reason for the importance of regulation of digestive secretions in the overall process of digestion. Also, the problem that occurs without regulation is to be determined.

Introduction:

Digestion is a fascinating process in which the person takes in the food, which is further utilized for energy production. This complete process takes place in the gastrointestinal tract that starts from the mouth and ends with the anus.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
You implant an FGF10-coated bead into the anterior flank of a chicken embryo, directly below the level of the wing bud. What is the phenotype of the resulting ectopic limb?  Briefly describe the expected expression domains of 1) Shh, 2) Tbx4, and 3) Tbx5 in the resulting ectopic limb bud.

Chapter 9 Solutions

HUMAN BIOLOGY (LOOSELEAF)

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