Biology: Concepts and Investigations
3rd Edition
ISBN: 9780073525549
Author: Mariëlle Hoefnagels Dr.
Publisher: McGraw-Hill Education
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Chapter 9.3, Problem 4MC
Summary Introduction
To explain:
The term zygote.
Concept introduction:
The cell is the basic functional and structural unit of life. The cells are of two different types, namely eukaryotes and prokaryotes. The eukaryotic cell contains a membrane-bound nuclei and double membrane-bound organelles. The prokaryotic cell lacks any double membrane-bound organelle. The zygote is a eukaryotic cell formed in some protozoa,
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 9 Solutions
Biology: Concepts and Investigations
Ch. 9.1 - Prob. 1MCCh. 9.1 - How can asexually reproducing organisms acquire...Ch. 9.1 - Prob. 3MCCh. 9.2 - Prob. 1MCCh. 9.2 - 2. Draw a hypothetical karyotype for a cell with a...Ch. 9.3 - How do haploid and diploid nuclei differ?Ch. 9.3 - Prob. 3MCCh. 9.3 - Prob. 4MCCh. 9.3 - Prob. 1MCCh. 9.4 - What happens during interphase
Ch. 9.4 - How do the events of meiosis I and meiosis II...Ch. 9.5 - Prob. 1MCCh. 9.5 - Prob. 2MCCh. 9.5 - How are identical twins different from fraternal...Ch. 9.6 - Prob. 1MCCh. 9.6 - In what ways are mitosis and meiosis different?Ch. 9.7 - Prob. 1MCCh. 9.7 - How can deletions, duplications, inversions, and...Ch. 9.8 - What are the stages of sperm development in...Ch. 9.8 - Prob. 2MCCh. 9.8 - How does gamete production in plants differ from...Ch. 9.9 - Prob. 1MCCh. 9.9 - Prob. 2MCCh. 9 - Prob. 1MCQCh. 9 - Prob. 2MCQCh. 9 - Meiosis explains why a. you inherited half of your...Ch. 9 - Prob. 4MCQCh. 9 - Prob. 5MCQCh. 9 - Prob. 6MCQCh. 9 - Prob. 7MCQCh. 9 - Explain why evolution often selects traits that...Ch. 9 - Describe a situation in which asexual reproduction...Ch. 9 - Prob. 3WIOCh. 9 - Sketch the relationships among mitosis, meiosis,...Ch. 9 - Prob. 5WIOCh. 9 - Prob. 6WIOCh. 9 - Prob. 7WIOCh. 9 - Draw all possible metaphase I chromosomal...Ch. 9 - Prob. 9WIOCh. 9 - List examples of abnormalities in chromosome...Ch. 9 - Prob. 11WIOCh. 9 - Prob. 12WIOCh. 9 - Prob. 13WIOCh. 9 - 2. Fit the following terms into this concept map:...Ch. 9 - 3. Create a separate concept map that includes...Ch. 9 -
3. What two processes in meiosis I generate...
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