Whether anaerobic respiration or fermentation would yield more ATP. Concept Introduction: Both anaerobic respiration and fermentation enable the cells to form ATP in the absence of oxygen.

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Chapter 9, Problem 9.5CR

Summary Introduction

To analyze: Whether anaerobic respiration or fermentation would yield more ATP.

Concept Introduction:

Both anaerobic respiration and fermentation enable the cells to form ATP in the absence of oxygen.

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1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine: (a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip MAKE SURE ANSWERS HAVE UNITS if appropriate. SHOW ALL WORK, including equation used, variables used and each step to your solution.

2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0 Note that a µCi is a measure of the amount of radioactivity and hence is a measure of the amount of drug present. Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this…

The current nutrition labelling regulation in Hong Kong requires food manufacturer to list E+7 information on the package of pre-packaged food products. Do you think that more nutrients, such as calcium and cholesterol, shall be included?

Answer 2

Question

Chapter 9, Problem 9.5CR

Summary Introduction

To analyze: Whether anaerobic respiration or fermentation would yield more ATP.

Concept Introduction:

Both anaerobic respiration and fermentation enable the cells to form ATP in the absence of oxygen.

Expert Solution & Answer

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Answer 3

Question

Chapter 9, Problem 9.5CR

Summary Introduction

To analyze: Whether anaerobic respiration or fermentation would yield more ATP.

Concept Introduction:

Both anaerobic respiration and fermentation enable the cells to form ATP in the absence of oxygen.

Expert Solution & Answer

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Answer 4

Question

Chapter 9, Problem 9.5CR

Summary Introduction

To analyze: Whether anaerobic respiration or fermentation would yield more ATP.

Concept Introduction:

Both anaerobic respiration and fermentation enable the cells to form ATP in the absence of oxygen.

Expert Solution & Answer

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Answer 5

Chapter 9, Problem 9.5CR

Summary Introduction

To analyze: Whether anaerobic respiration or fermentation would yield more ATP.

Concept Introduction:

Both anaerobic respiration and fermentation enable the cells to form ATP in the absence of oxygen.

Answer 6

Chapter 9, Problem 9.5CR

Summary Introduction

To analyze: Whether anaerobic respiration or fermentation would yield more ATP.

Concept Introduction:

Both anaerobic respiration and fermentation enable the cells to form ATP in the absence of oxygen.

Answer 7

Chapter 9, Problem 9.5CR

Summary Introduction

To analyze: Whether anaerobic respiration or fermentation would yield more ATP.

Concept Introduction:

Both anaerobic respiration and fermentation enable the cells to form ATP in the absence of oxygen.

Answer 8

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Answer 9

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Answer 11

Ch. 9.1 - Compare and contrast aerobic and anaerobic...Ch. 9.1 - WHAT IF? If the following redox reaction...Ch. 9.2 - Prob. 1CC Ch. 9.3 - Prob. 1CC Ch. 9.3 - What process in your cells produce the CO2 that...Ch. 9.3 - Prob. 3CC Ch. 9.4 - Prob. 1CC Ch. 9.4 - WHAT IF? In the absence of O2 as in question 1,...Ch. 9.4 - MAKE CONNECTIONS Membranes must be fluid to...Ch. 9.5 - Consider the NADH formed during glycolysis. What...

Whether anaerobic respiration or fermentation would yield more ATP. Concept Introduction: Both anaerobic respiration and fermentation enable the cells to form ATP in the absence of oxygen.

Solution Summary: The author explains that both anaerobic respiration and fermentation use glycolysis to oxidize glucose, but they differ in their final electron acceptor depending on the presence of oxygen.

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To analyze: Whether anaerobic respiration or fermentation would yield more ATP.

Concept Introduction:

Both anaerobic respiration and fermentation enable the cells to form ATP in the absence of oxygen.

Want to see the full answer?

Chapter 9 Solutions

Whether anaerobic respiration or fermentation would yield more ATP. Concept Introduction: Both anaerobic respiration and fermentation enable the cells to form ATP in the absence of oxygen.

Solution Summary: The author explains that both anaerobic respiration and fermentation use glycolysis to oxidize glucose, but they differ in their final electron acceptor depending on the presence of oxygen.

Videos

To analyze: Whether anaerobic respiration or fermentation would yield more ATP. Concept Introduction: Both anaerobic respiration and fermentation enable the cells to form ATP in the absence of oxygen.

Want to see the full answer?

Chapter 9 Solutions

To analyze: Whether anaerobic respiration or fermentation would yield more ATP.

Concept Introduction:

Both anaerobic respiration and fermentation enable the cells to form ATP in the absence of oxygen.