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Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Question
Chapter 9, Problem 4TYK
Summary Introduction
Introduction:
Tyrosine kinase is a receptor present in the plasma membrane. When these are bound by signals, receptors cause the autophosphorylation of protein kinases that results in its activation. These activated tyrosine kinases provide sites for binding of intracellular receptor, which then initiates the cascade and produces response.
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Students have asked these similar questions
In the antibody-mediated immune response, the binding of some antigen-presenting B
cells to helper T cells initiates a signal transduction pathway that transforms the B cells into
plasma cells, which will synthesize and secrete large quantities of antibodies-a specialized
subset of proteins responsible for attaching to the antigen on the outer surface of
pathogens.
Which of the following describes the most relevant intracellular change to B cells as they
are transformed into plasma cells?
A
B
a breakdown of some membrane-bound proteins to allow synthesized antibodies to
more readily diffuse across the membrane of the plasma cell
с
an increase in the surface area of the rough endoplasmic reticulum in order to allow the
binding of a large number of ribosomes for antibody synthesis
D
an increase in the number of lysosomes in order to facilitate the storage of synthesized
antibodies ahead of their transport out of the cell
an increase in the volume of the mitochondria in order to increase…
All except which one of the following can be a function of the heterotrimeric G protein of a GPCR?
a)
inhibit adenylyl cyclase
b)
activate adenylyl cyclase
c)
act as a protein kinase
d)
activate ion channels
It is important for the cell to be able to terminate responses, and diminish responsiveness to prevent overstimulation. Cells have different mechanisms for this. One such mechanism is receptor down regulation.
a.) Down regulation describes a decrease in the availability of hormones or neurotransmitters that bind to receptors on the surface of target cells, making the cells less likely to be stimulated.
b.) Down regulation describes glycosylation of receptor proteins receptors on the surface of target cells in order to decrease the selectivity of ligand binding, making the cells less sensitive to a hormone or neurotransmitter.
c.) Down regulation describes a decrease in the number of receptors on the surface of target cells, making the cells less sensitive to a hormone or neurotransmitter.
Chapter 9 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 9.1 - What accounts for the specificity of a cellular...Ch. 9.2 - Prob. 1SBCh. 9.2 - Prob. 2SBCh. 9.3 - Prob. 1SBCh. 9.3 - Prob. 2SBCh. 9.3 - Prob. 3SBCh. 9.3 - Prob. 4SBCh. 9.3 - Prob. 5SBCh. 9.3 - Prob. 6SBCh. 9.4 - What distinguishes a steroid receptor from a...
Ch. 9.4 - By what means does a specific steroid hormone...Ch. 9.5 - Prob. 1SBCh. 9 - In signal transduction, which of the following is...Ch. 9 - Which of the following could not elicit a signal...Ch. 9 - A cell that responds to a signaling molecule is...Ch. 9 - Prob. 4TYKCh. 9 - Prob. 5TYKCh. 9 - Which of the following is incorrect about pathways...Ch. 9 - Which of the following would not inhibit signal...Ch. 9 - Prob. 8TYKCh. 9 - Prob. 9TYKCh. 9 - Prob. 10TYKCh. 9 - Discuss Concepts Describe the possible ways in...Ch. 9 - Discuss Concepts Is providing extra insulin an...Ch. 9 - Discuss Concepts There are molecules called GTP...Ch. 9 - Discuss Concepts Why do you suppose cells evolved...Ch. 9 - How would you set up an experiment to determine...Ch. 9 - Prob. 16TYKCh. 9 - Prob. 1ITDCh. 9 - Prob. 2ITDCh. 9 - Prob. 3ITD
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- In intercellular signaling pathways, some receptor proteins can also act as a transcription factor (changing gene expression), because these receptors are ________. A) Group of answer choices B) Intracellular receptors C) Membrane bound receptors D) G protein coupled receptors E) Enzyme linked receptors F) Fast ligand-gated ion channelsarrow_forwardCTLs use the following membrane-bound protein interactions to “kill” a target cell through apoptosis: Question 8 options: A) IL-2/IL-2 receptor B) CD4/MHC II C) TCR/MHC II D) Fas/FasLarrow_forwardTumor necrosis factor alpha (TNF-α) is an important cytokine used by immune cells to initiate and coordinate inflammatory responses. Inflammation is a key response to cell damage or infection, but can, in some diseases, spiral out of control and become more of a problem than the original cause (COVID-19 lung damage is a relevant example...). TNF-α receptors exist on many cell types. Let’s study the interaction between TNF-α (T) and its receptor (R), to form an activated complex C: T + R ↔ C A macrophage is measured to have ~105 TNF-α receptors on its surface. If the macrophage is immersed in a high concentration of TNF-α molecules (i.e. L0 ≅ L), how will the number of activated receptors change over time? Plot this trend for the case L0 =10 nM, kf=106 M-1 min-1, kr=0.1 min-1. There is constant ligand concentration and an initial condition of C0 = 0. We are given the constants needed to model the number of activated receptors over time and can use the following equation:arrow_forward
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