Biochemistry 410/411 Textbook - 5th Edition - Custom Texas A&M University
5th Edition
ISBN: 9781119302940
Author: Voet
Publisher: WILEY C
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Chapter 9, Problem 31CQ
Summary Introduction
To explain: The reason why excessive macropinocytosis would lead to cell death.
Concept introduction: Macropinocytosis is a regulated form of endocytosis. It mediates the non-selective uptake of solute molecules, nutrients and antigens. In the macrophages and the dendritic cells, macropinocytosis is a chief pathway for the capture of antigens. Also, it is relevant to tumor metastasis and cell migration.
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Two tetrapeptides were isolated from a possum's sweat glands. These peptides were sequenced using Edman degradation and the following 2 sequences were obtained:
Gly-Asp-Ala-Leu
Gly-Asp-Asp-Leu
What is the structure of the PTH derivative produced during the last round of amino acid sequencing?
What is the primary sequence of this undecapeptide? Also, if x-ray crystallography shows a highly stable hairpin turn within the polypeptide, what about the primary sequence explains this structural feature?
Draw the product of this reaction.
Ignore inorganic byproducts.
H
H ⚫OH
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-H
H-
-OH
H-
-OH
CH2OH
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Chapter 9 Solutions
Biochemistry 410/411 Textbook - 5th Edition - Custom Texas A&M University
Ch. 9 - Prob. 1ECh. 9 - 2. Which triacylglycerol yields more energy on...Ch. 9 - 3. Draw the structure of a glycerophospholipid...Ch. 9 - 4. Name this lipid.
Ch. 9 - Prob. 5ECh. 9 - 6. What products are obtained when...Ch. 9 - 7. Which of the glycerophospholipid head groups...Ch. 9 - Prob. 8ECh. 9 - 9. Identify the hormone molecule shown here. What...Ch. 9 - 10. Draw the structure of the fatty acid amide...
Ch. 9 - Prob. 11ECh. 9 - Prob. 12ECh. 9 - Prob. 13ECh. 9 - Prob. 14ECh. 9 - Prob. 15ECh. 9 - Prob. 16ECh. 9 - 17. (a) How many turns of an ? helix are required...Ch. 9 - 18. The distance between successive C? atoms in a...Ch. 9 - 19. Are the following lipid samples likely to...Ch. 9 - 20. In order to consume and dispose of dying...Ch. 9 - 21. Sphingosine-1-phosphate can serve as a cell...Ch. 9 - 22. Lipids known as sulfatides occur in cells of...Ch. 9 - 23. In some autoimmune diseases, an individual...Ch. 9 - 24. Most hormones, such as peptide hormones, exert...Ch. 9 - 25. E. coli outer membranes include a component...Ch. 9 - 26. Archaebacteria and Eubacteria produce...Ch. 9 - 27. Shigella bacteria cause severe diarrhea by...Ch. 9 - 28. The inner membranes of mitochondria are rich...Ch. 9 - 29. Describe the labeling pattern of glycophorin....Ch. 9 - 30. Identify a 20-residue segment that could form...Ch. 9 - 31. Macropinocytosis is a variation of endocytosis...Ch. 9 - 32. Explain why the action of phospholipase A2 on...Ch. 9 - 33. Predict the effect of a mutation in signal...Ch. 9 - 34. Explain why a drug that interferes with the...Ch. 9 - 35. The symmetries of oligomeric integral proteins...Ch. 9 - Prob. 36CQCh. 9 - MORE TO EXPLORE Some of the more unusual membrane...
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