FUNDAMENTALS OF ANATOMY AND PHYSIOLOGY
11th Edition
ISBN: 2818440046582
Author: Martini
Publisher: PEARSON C
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Chapter 9, Problem 2RQ
Summary Introduction
Introduction:
Immovable joints are also called as synarthrosis, which means “together joint”. These joints can be either, cartilaginous or fibrous. It depends on the type of connections between the 2 bones. The 2 bones over the time, can even fuse or ossify. These joints are found in the axial skeleton.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 9 Solutions
FUNDAMENTALS OF ANATOMY AND PHYSIOLOGY
Ch. 9 - Name and describe the three types of joints as...Ch. 9 - What characteristics do typical synarthrotic and...Ch. 9 - In a newborn, the large bones of the skull are...Ch. 9 - Describe the components of a synovial joint, and...Ch. 9 - Why would improper circulation of synovial fluid...Ch. 9 - Prob. 6CPCh. 9 - Prob. 7CPCh. 9 - When you do jumping jacks, which lower limb...Ch. 9 - Prob. 9CPCh. 9 - Prob. 10CP
Ch. 9 - Which regions of the vertebral column lack...Ch. 9 - Prob. 12CPCh. 9 - Terry suffers an injury to his forearm and elbow....Ch. 9 - Prob. 14CPCh. 9 - Prob. 15CPCh. 9 - Prob. 16CPCh. 9 - Prob. 17CPCh. 9 - Would a tennis player or a jogger be more likely...Ch. 9 - A football player received a hit to the upper...Ch. 9 - Prob. 20CPCh. 9 - Prob. 21CPCh. 9 - Prob. 22CPCh. 9 - Define arthritis.Ch. 9 - Prob. 24CPCh. 9 - Describe the functional relationship between the...Ch. 9 - Prob. 1RQCh. 9 - Prob. 2RQCh. 9 - Prob. 3RQCh. 9 - Prob. 4RQCh. 9 - Prob. 5RQCh. 9 - Prob. 6RQCh. 9 - Prob. 7RQCh. 9 - Prob. 8RQCh. 9 - Prob. 9RQCh. 9 - Prob. 10RQCh. 9 - Prob. 11RQCh. 9 - Prob. 12RQCh. 9 - Prob. 13RQCh. 9 - Prob. 14RQCh. 9 - Prob. 15RQCh. 9 - Prob. 16RQCh. 9 - Prob. 17RQCh. 9 - Prob. 18RQCh. 9 - Prob. 19RQCh. 9 - Dislocations involving synovial joints are usually...Ch. 9 - Prob. 21RQCh. 9 - Prob. 22RQCh. 9 - Prob. 23RQCh. 9 - Prob. 24RQCh. 9 - Prob. 25RQCh. 9 - Prob. 26RQCh. 9 - Prob. 27RQCh. 9 - Prob. 28RQCh. 9 - Joe injures his knee during a football practice...Ch. 9 - When playing a contact sport, which injury would...Ch. 9 - Prob. 1CCCh. 9 - Prob. 2CC
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