The reason for large differences between the synonymous and nonsynonymous rates of nucleotide substitution. Introduction: A non-synonymous substitution is a nucleotide mutation that alters the amino acid sequence of a protein. It is contrasted with synonymous substitution or silent mutation, which do not alter the amino acid sequences.

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Answer 1

Question

Chapter 9, Problem 16Q

A.

Summary Introduction

To determine: The reason for large differences between the synonymous and nonsynonymous rates of nucleotide substitution.

Introduction: A non-synonymous substitution is a nucleotide mutation that alters the amino acid sequence of a protein. It is contrasted with synonymous substitution or silent mutation, which do not alter the amino acid sequences.

B.

Summary Introduction

To determine: The way in which it is possible for the histone H3 gene to resist so effectively the nucleotide changes that can alter its amino acid sequence, if the rates of synonymous changes are about the same for all genes.

Introduction: Histone proteins are highly conserved in eukaryotes. They are found almost in equal quantity as of DNA in a cell. Histone proteins are responsible for the packing of chromatin into nucleosome. There are five different families of histone protein. These are H1, H2A, H2B, H3 and H4.

C.

Summary Introduction

To determine: The feature of the data obtained from experiment on H3 protein argues against the highly privileged nature of this protein.

Introduction: H3 protein is one among the five histone proteins. It is a structural variant of the histone protein that is involved in packaging the DNA molecules into a structure called nucleosomes.

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Alleles at the P locus control seed color. Plants which are pp have white seeds, white flowers and no pigment in vegetative parts. Plants which are P_ have black seeds, purple flowers and may have varying degrees of pigment on stems and leaves. Seed color can be assessed, visually, based on if the seed is white or not white A gene for mold resistance has been reported and we want to determine its inheritance and whether it is linked to P. For the purposes of this exercise, we will assume that resistance is controlled by a single locus M, and M_ plants are resistant and mm plants are susceptible. Resistance can be measured, under greenhouse conditions, 2 weeks after planting, by injecting each seedling with a spore suspension. After two weeks, the seedlings can be rated as resistant or susceptible, based on whether or not tissue is actively sporulating. For this exercise we will use seed and data from the F10 generation of a recombinant inbred population produced using single seed…

Answer 2

Question

Chapter 9, Problem 16Q

A.

Summary Introduction

To determine: The reason for large differences between the synonymous and nonsynonymous rates of nucleotide substitution.

Introduction: A non-synonymous substitution is a nucleotide mutation that alters the amino acid sequence of a protein. It is contrasted with synonymous substitution or silent mutation, which do not alter the amino acid sequences.

B.

Summary Introduction

To determine: The way in which it is possible for the histone H3 gene to resist so effectively the nucleotide changes that can alter its amino acid sequence, if the rates of synonymous changes are about the same for all genes.

Introduction: Histone proteins are highly conserved in eukaryotes. They are found almost in equal quantity as of DNA in a cell. Histone proteins are responsible for the packing of chromatin into nucleosome. There are five different families of histone protein. These are H1, H2A, H2B, H3 and H4.

C.

Summary Introduction

To determine: The feature of the data obtained from experiment on H3 protein argues against the highly privileged nature of this protein.

Introduction: H3 protein is one among the five histone proteins. It is a structural variant of the histone protein that is involved in packaging the DNA molecules into a structure called nucleosomes.

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Answer 3

Question

Chapter 9, Problem 16Q

A.

Summary Introduction

To determine: The reason for large differences between the synonymous and nonsynonymous rates of nucleotide substitution.

Introduction: A non-synonymous substitution is a nucleotide mutation that alters the amino acid sequence of a protein. It is contrasted with synonymous substitution or silent mutation, which do not alter the amino acid sequences.

B.

Summary Introduction

To determine: The way in which it is possible for the histone H3 gene to resist so effectively the nucleotide changes that can alter its amino acid sequence, if the rates of synonymous changes are about the same for all genes.

Introduction: Histone proteins are highly conserved in eukaryotes. They are found almost in equal quantity as of DNA in a cell. Histone proteins are responsible for the packing of chromatin into nucleosome. There are five different families of histone protein. These are H1, H2A, H2B, H3 and H4.

C.

Summary Introduction

To determine: The feature of the data obtained from experiment on H3 protein argues against the highly privileged nature of this protein.

Introduction: H3 protein is one among the five histone proteins. It is a structural variant of the histone protein that is involved in packaging the DNA molecules into a structure called nucleosomes.

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Answer 4

Question

Chapter 9, Problem 16Q

A.

Summary Introduction

To determine: The reason for large differences between the synonymous and nonsynonymous rates of nucleotide substitution.

Introduction: A non-synonymous substitution is a nucleotide mutation that alters the amino acid sequence of a protein. It is contrasted with synonymous substitution or silent mutation, which do not alter the amino acid sequences.

B.

Summary Introduction

To determine: The way in which it is possible for the histone H3 gene to resist so effectively the nucleotide changes that can alter its amino acid sequence, if the rates of synonymous changes are about the same for all genes.

Introduction: Histone proteins are highly conserved in eukaryotes. They are found almost in equal quantity as of DNA in a cell. Histone proteins are responsible for the packing of chromatin into nucleosome. There are five different families of histone protein. These are H1, H2A, H2B, H3 and H4.

C.

Summary Introduction

To determine: The feature of the data obtained from experiment on H3 protein argues against the highly privileged nature of this protein.

Introduction: H3 protein is one among the five histone proteins. It is a structural variant of the histone protein that is involved in packaging the DNA molecules into a structure called nucleosomes.

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Answer 5

Chapter 9, Problem 16Q

A.

Summary Introduction

To determine: The reason for large differences between the synonymous and nonsynonymous rates of nucleotide substitution.

Introduction: A non-synonymous substitution is a nucleotide mutation that alters the amino acid sequence of a protein. It is contrasted with synonymous substitution or silent mutation, which do not alter the amino acid sequences.

B.

Summary Introduction

To determine: The way in which it is possible for the histone H3 gene to resist so effectively the nucleotide changes that can alter its amino acid sequence, if the rates of synonymous changes are about the same for all genes.

Introduction: Histone proteins are highly conserved in eukaryotes. They are found almost in equal quantity as of DNA in a cell. Histone proteins are responsible for the packing of chromatin into nucleosome. There are five different families of histone protein. These are H1, H2A, H2B, H3 and H4.

C.

Summary Introduction

To determine: The feature of the data obtained from experiment on H3 protein argues against the highly privileged nature of this protein.

Introduction: H3 protein is one among the five histone proteins. It is a structural variant of the histone protein that is involved in packaging the DNA molecules into a structure called nucleosomes.

Answer 6

Chapter 9, Problem 16Q

A.

Summary Introduction

To determine: The reason for large differences between the synonymous and nonsynonymous rates of nucleotide substitution.

Introduction: A non-synonymous substitution is a nucleotide mutation that alters the amino acid sequence of a protein. It is contrasted with synonymous substitution or silent mutation, which do not alter the amino acid sequences.

Answer 7

Chapter 9, Problem 16Q

A.

Summary Introduction

To determine: The reason for large differences between the synonymous and nonsynonymous rates of nucleotide substitution.

Introduction: A non-synonymous substitution is a nucleotide mutation that alters the amino acid sequence of a protein. It is contrasted with synonymous substitution or silent mutation, which do not alter the amino acid sequences.

Answer 8

B.

Summary Introduction

To determine: The way in which it is possible for the histone H3 gene to resist so effectively the nucleotide changes that can alter its amino acid sequence, if the rates of synonymous changes are about the same for all genes.

Introduction: Histone proteins are highly conserved in eukaryotes. They are found almost in equal quantity as of DNA in a cell. Histone proteins are responsible for the packing of chromatin into nucleosome. There are five different families of histone protein. These are H1, H2A, H2B, H3 and H4.

Answer 9

B.

Summary Introduction

To determine: The way in which it is possible for the histone H3 gene to resist so effectively the nucleotide changes that can alter its amino acid sequence, if the rates of synonymous changes are about the same for all genes.

Introduction: Histone proteins are highly conserved in eukaryotes. They are found almost in equal quantity as of DNA in a cell. Histone proteins are responsible for the packing of chromatin into nucleosome. There are five different families of histone protein. These are H1, H2A, H2B, H3 and H4.

Answer 10

C.

Summary Introduction

To determine: The feature of the data obtained from experiment on H3 protein argues against the highly privileged nature of this protein.

Introduction: H3 protein is one among the five histone proteins. It is a structural variant of the histone protein that is involved in packaging the DNA molecules into a structure called nucleosomes.

Answer 11

C.

Summary Introduction

To determine: The feature of the data obtained from experiment on H3 protein argues against the highly privileged nature of this protein.

Introduction: H3 protein is one among the five histone proteins. It is a structural variant of the histone protein that is involved in packaging the DNA molecules into a structure called nucleosomes.

Answer 12

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Ch. 9 - Prob. 1Q Ch. 9 - Prob. 2Q Ch. 9 - Prob. 3Q Ch. 9 - Prob. 4Q Ch. 9 - Prob. 5Q Ch. 9 - Prob. 6Q Ch. 9 - Prob. 7Q Ch. 9 - Prob. 8Q Ch. 9 - Prob. 9Q Ch. 9 - Prob. 10Q

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