Campbell Biology in Focus (2nd Edition)
2nd Edition
ISBN: 9780321962751
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Textbook Question
Chapter 9, Problem 10TYU
SYNTHESIZE YOUR KNOWLEDGE
Shown here are two He La cancer cells that are just completing cytokinesis. Explain how the cell division of cancer cells like these is misregulated. What genetic and other changes might have caused these cells to escape normal cell cycle regulation?
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Chapter 9 Solutions
Campbell Biology in Focus (2nd Edition)
Ch. 9.1 - WHAT IF? A chicken has 78 chromosomes in its...Ch. 9.2 - Compare cytokinesis in animal cells and plant...Ch. 9.2 - Prob. 3CCCh. 9.2 - Compare the roles of tubulin and actin during...Ch. 9.3 - Prob. 1CCCh. 9.3 - Prob. 2CCCh. 9.3 - Compare and contrast a benign tumor and a...Ch. 9.3 - Prob. 4CCCh. 9 - Through a microscope, you can see a cell plate...Ch. 9 - In the cells of some organisms, mitosis occurs...
Ch. 9 - Which of the following does not occur during...Ch. 9 - Prob. 4TYUCh. 9 - The drug cytochalasin B blocks the function of...Ch. 9 - DRAW IT Draw one eukaryotic chromosome as it would...Ch. 9 - The light micrograph shows dividing cells near the...Ch. 9 - SCIENTIFIC INQUIRY Although both ends of a...Ch. 9 - FOCUS ON EVOLUTION The result of mitosis is that...Ch. 9 - SYNTHESIZE YOUR KNOWLEDGE Shown here are two He La...Ch. 9 - FOCUS ON INFORMATION The continuity of life is...
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- Hi, can you explain this concept: cell cycle progression can be halted at several points by the tumor suppressor gene product p53, activated in response to checkpoints sensing DNA and possibly also chromosome damage; loss of p53 would remove this brake to cycling. How these events can lead to cancer progression?arrow_forwardplease explainarrow_forwardFigure 28.11 depicts the eukaryotic cell cycle. Many cell types “exit� the cell cycle and don’t divide for prolonged periods, a state termedG0; some, for example neurons, never divide again. a. In what stage of the cell cycle do you suppose a cell might be when it exits the cell cycle and enters G0? b. The cell cycle is controlled by checkpoints, cyclins, and CDKs. Describe how biochemical events involving cyclins and CDKs might control passage of a dividing cell through the cell cycle.arrow_forward
- Figure 10.13 Rb and other proteins that negatively regulate the cell cycle are sometimes called tumor suppressors. Why do you think the name tumor suppressor might be appropriate for these proteins?arrow_forwardChoose one of these answersarrow_forwardArtificially induced apoptosis (controlled cellular death) is found to be an effective treat- ment for some forms of cancer. Which of the following describes the most likely mechanism by which apoptosis might be induced? A B с D by causing ribosomes to increase the rate of protein synthesis by triggering the division of mitochondria in the cell to increase ATP production by increasing the expression of membrane-bound glucose protein channels by causing lysosomes to release digestive enzymes into the cytosolarrow_forward
- Discuss the complete cell cycle in a human cell, mitosis and meiosis, and the regulatory components (i.e. the proteins associated with cellular checkpoints) of the cell cycle. Tumor growth results when the cell cycle checkpoints are ignored. Give an example of how tumor growth could result from either a loss-of-function or a gain-of-function mutation.arrow_forwardBriefly describe the cell cycle, its checkpoints, and the general proteins required to move past each checkpoint. For each cell cycle checkpoint, be sure to describe what the cell is "checking for" and how this "check" occurs, along with the result if the checkpoint cannot be passed. Your answer should also include a description of the structure of MPF, its regulation, and its general targets or functions. Be sure to include any accessory molecules or proteins involved in regulation of MPF, while also describing the process by which MPF is formed and activated. In this answer, you should also choose two proteins involved in the cell cycle, which, if mutated, will cause cancer. Describe these proteins and their normal functions, and then show how a mutation in these proteins will result in cancer.arrow_forwardWhat role do aurora kinase play in the cell cycle and how would using these kinases as target for cancer treated work?arrow_forward
- In your own words, explain how cancer cells differ from normal cells in regard to the following: Molecular controls of the cell cycle (include Cdk and Cdk/cyclin complexes, p53 gene/protein, Rb gene/protein in response)arrow_forwardShown here are two HeLa cancer cells that are just completing cytokinesis. Explain how the cell division of cancer cellslike these is misregulated. Identify genetic and other changesthat might have caused these cells to escape normal cell cycleregulationarrow_forwardlook at the screenshot pleasearrow_forward
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cell division of meiosis and mitosis; Author: Stated Clearly;https://www.youtube.com/watch?v=A-mFPZLLbHI;License: Standard youtube license