Anatomy & Physiology (6th Edition)
Anatomy & Physiology (6th Edition)
6th Edition
ISBN: 9780134156415
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Chapter 8.3, Problem 4CYU
Summary Introduction

To review:

The chances for the presence of synchondroses at the ends of the femur in a 25-year-old boy.

Introduction:

The three structural classes of joints are fibrous, cartilaginous, and synovial joints, depending upon the presence of the joint cavity and the binding material that connects the bones together. The joint cavity is only present in case of synovial joints. The binding material in fibrous joints is collagen fibers, cartilage in the cartilaginous joint, and dense irregular connective tissue (articular capsule) in synovial joints.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

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Anatomy & Physiology (6th Edition)

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