Macroscale and Microscale Organic Experiments
Macroscale and Microscale Organic Experiments
7th Edition
ISBN: 9781305577190
Author: Kenneth L. Williamson, Katherine M. Masters
Publisher: Brooks Cole
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Chapter 8, Problem 9Q
Interpretation Introduction

Interpretation:

The appearance of the spots on the TLC plate in case of the solvent of low and high polarities should be determined.

Concept introduction:

TLC works on the principle of separation of constituents of a mixture of compounds based on polarity. The polar compounds interact with the stationary phase thus can move to smaller distance from the base. While the non-polar compounds tend to move faster as they interact less with the silica gel, therefore, they move far from the base of the plate.

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What will be the appearance of a TLC plate if a solvent of too low polarity is used for the development? too high polarity?
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