Lehninger Principles Of Biochemistry 7e & Study Guide And Solutions Manual For Lehninger Principles Of Biochemistry 7e
Lehninger Principles Of Biochemistry 7e & Study Guide And Solutions Manual For Lehninger Principles Of Biochemistry 7e
7th Edition
ISBN: 9781319125776
Author: David L. Nelson, Michael M. Cox
Publisher: W. H. Freeman
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Chapter 8, Problem 8P
Summary Introduction

To determine: The chemical consequence of base loss along with examination of AP site structure.

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The abnormal chemical sequence in the DNA represents the DNA damage, while the mutation of the DNA is a change in the sequence of standard DNA base pairs. A thermodynamic destabilization created by an AP site creates is more as compared to destabilization created by mismatched base pair. In DNA an AP site is created by the hydrolysis of N-glycosyl bond which is present between deoxyribose and a purine base.

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