
Concept explainers
To determine: The positions in the purine ring of a purine
Introduction:
There are two types of nitrogenous bases: purines and pyrimidines. Adenine and guanine are the purine bases with double ring structures. Cytosine and thymine are the pyrimidines bases that have single ring structure. These bases pair with their complementary bases and form a nucleotide sequence through hydrogen bonding.

Explanation of Solution
Explanation:
Adenine is linked to thymine with double hydrogen bond and guanine is linked to cytosine with triple hydrogen bond. The two nucleotides are joined together by the phosphodiester bond.
Purine is a structure that contains nine member ring which is made up of a imidazole ring along with a pyrimidine ring. In adenine amino group present at the sixth position along with first position’s nitrogen is involved in Watson-Crick base pairing with complementary pyrimidine base which is thymine.
In guanine, nitrogen present at first position and amino group at second carbon along with oxo group at sixth carbon is involved in Watson-Crick base pairing with complementary pyrimidine base which is cytosine.
Thus, the positions of purine ring that have the property to form hydrogen bonds but do not participate in Watson-Crick base pairing are the nitrogen which is present at third and seventh position of purine ring.
Conclusion:
Third and seventh positions in purine ring are involved in hydrogen bonding but do not involve in Watson-Crick base pairing.
Want to see more full solutions like this?
Chapter 8 Solutions
Lehninger Principles of Biochemistry
- Show a mechanism that leads to the opening of the ring below under acid-catalyzed conditions. Give the correct Fischer projection for this sugar.arrow_forwardWhat is the stereochemical relationship between B & C?arrow_forwardDon't use ai or any chat gpt will dislike okk just use accurate information okkk okkk just solve full accurate. don't use guidelines okk just did it accurate 100% sure experts solve it correct complete solutions okkk follow all instructions requirements okkkarrow_forward
- Problem 15 of 15 Submit Using the following reaction data points, construct Lineweaver-Burk plots for an enzyme with and without an inhibitor by dragging the points to their relevant coordinates on the graph and drawing a line of best fit. Using the information from this plot, determine the type of inhibitor present. 1 mM-1 1 s mM -1 [S]' V' with 10 μg per 20 54 10 36 20 5 27 2.5 23 1.25 20 Answer: |||arrow_forward12:33 CO Problem 4 of 15 4G 54% Done On the following Lineweaver-Burk -1 plot, identify the by dragging the Km point to the appropriate value. 1/V 40 35- 30- 25 20 15 10- T Км -15 10 -5 0 5 ||| 10 15 №20 25 25 30 1/[S] Г powered by desmosarrow_forward1:30 5G 47% Problem 10 of 15 Submit Using the following reaction data points, construct a Lineweaver-Burk plot for an enzyme with and without a competitive inhibitor by dragging the points to their relevant coordinates on the graph and drawing a line of best fit. 1 -1 1 mM [S]' s mM¹ with 10 mg pe 20 V' 54 10 36 > ст 5 27 2.5 23 1.25 20 Answer: |||arrow_forward
- BiochemistryBiochemistryISBN:9781319114671Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.Publisher:W. H. FreemanLehninger Principles of BiochemistryBiochemistryISBN:9781464126116Author:David L. Nelson, Michael M. CoxPublisher:W. H. FreemanFundamentals of Biochemistry: Life at the Molecul...BiochemistryISBN:9781118918401Author:Donald Voet, Judith G. Voet, Charlotte W. PrattPublisher:WILEY
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage LearningBiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage LearningFundamentals of General, Organic, and Biological ...BiochemistryISBN:9780134015187Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. PetersonPublisher:PEARSON





