Chapter 7.6, Problem 11CC

(a)

Interpretation Introduction

Interpretation:

Rate of the reaction should be predicted at given the concentration of substrate and reagent for a second order reaction.

Concept Introduction:

• Elimination reaction: In elimination reaction, two substituents are removed from the substrate to give the product in presence of base.  Elimination reactions are two types, $E1$ and $E2$.
• $E1$ reaction: elimination follows stepwise mechanism.  Rate of the reaction depends only on substrate concentration.
  • $\text{r}\propto \text{[substrate]}$
• $E2$ reaction: elimination follows concerted pathway of mechanism.  Rate of the reaction depends on both substrates as well as reagent concentration.
  • $\text{r}\propto \text{[substrate]}\left[\text{base}\right]$
• Elimination of compound in presence of bulky base leads to less substituted alkene, in presence of strong base (not bulky) leads to more substituted alkene.

(b)

Interpretation Introduction

Interpretation:

Rate of the reaction should be predicted at given the concentration of substrate and reagent for a second order reaction.

Concept Introduction:

• Elimination reaction: In elimination reaction, two substituents are removed from the substrate to give the product in presence of base. Elimination reactions are two types, $E1$ and $E2$.
• $E1$ reaction: elimination follows stepwise mechanism. Rate of the reaction depends only on substrate concentration.
  • $\text{r}\propto \text{[substrate]}$
• $E2$ reaction: elimination follows concerted pathway of mechanism. Rate of the reaction depends on both substrates as well as reagent concentration.
  • $\text{r}\propto \text{[substrate]}\left[\text{base}\right]$
• Elimination of compound in presence of bulky base leads to less substituted alkene, in presence of strong base (not bulky) leads to more substituted alkene.

(c)

Interpretation Introduction

Interpretation:

Rate of the reaction should be predicted at given the concentration of substrate and reagent for a second order reaction.

Concept Introduction:

• Elimination reaction: In elimination reaction, two substituents are removed from the substrate to give the product in presence of base. Elimination reactions are two types, E1 and E2.
• $E1$ reaction: elimination follows stepwise mechanism. Rate of the reaction depends only on substrate concentration.
  • $\text{r}\propto \text{[substrate]}$
• $E2$ reaction: elimination follows concerted pathway of mechanism. Rate of the reaction depends on both substrates as well as reagent concentration.
  • $\text{r}\propto \text{[substrate]}\left[\text{base}\right]$
• Elimination of compound in presence of bulky base leads to less substituted alkene, in presence of strong base (not bulky) leads to more substituted alkene.