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Prescott's Microbiology
11th Edition
ISBN: 9781260211887
Author: WILLEY, Sandman, Wood
Publisher: McGraw Hill
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Chapter 7.4, Problem 1CC
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Define microbial growth.
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2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0
Note that a µCi is a measure of the amount of radioactivity and hence is a measure of the amount of drug present. Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this…
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Chapter 7 Solutions
Prescott's Microbiology
Ch. 7.1 - MICRO INQUIRY In addition to chromosomes, what...Ch. 7.2 - MICRO INQUIRY Why is it important that the origin...Ch. 7.2 - MICRO INQUIRY What would be the outcome if FtsZ...Ch. 7.2 - MICRO INQUIRY Which step in the development of...Ch. 7.2 - Retrieve, Infer, Apply 1. Describe the three...Ch. 7.2 - Retrieve, Infer, Apply 2. How does the bacterial...Ch. 7.2 - Retrieve, Infer, Apply 3. Do you think MinCDE...Ch. 7.2 - Retrieve, Infer, Apply 4. Do you think Spiroplasma...Ch. 7.3 - What elements of the Sulfolobus spp. cell cycle...Ch. 7.3 - Many archaea have genes encoding an FtsZ...
Ch. 7.4 - MICRO INQUIRY Identify the regions of the growth...Ch. 7.4 - Retrieve, Infer, Apply Define microbial growth.Ch. 7.4 - Retrieve, Infer, Apply Describe the phases of the...Ch. 7.4 - Why would cells that are vigorously growing when...Ch. 7.4 - Calculate the growth rate constant and generation...Ch. 7.4 - Suppose the generation time of a bacterium is 90...Ch. 7.5 - What is the difference between halophilic and...Ch. 7.5 - Why do facultative anaerobes grow best at the...Ch. 7.5 - Retrieve, Infer, Apply 1. How do microorganisms...Ch. 7.5 - Retrieve, Infer, Apply 2. Define water activity...Ch. 7.5 - Prob. 1.3CCCh. 7.5 - Retrieve, Infer, Apply 1. Define pH, acidophile,...Ch. 7.5 - Retrieve, Infer, Apply Classify each of the...Ch. 7.5 - Retrieve, Infer, Apply 3. Describe the mechanisms...Ch. 7.5 - Retrieve, Infer, Apply 1. What are cardinal...Ch. 7.5 - Prob. 3.2CCCh. 7.5 - Prob. 3.3CCCh. 7.5 - Prob. 3.4CCCh. 7.5 - Retrieve, Infer, Apply Describe the five types of...Ch. 7.5 - Retrieve, Infer, Apply What are the toxic effects...Ch. 7.5 - Retrieve, Infer, Apply Where would you expect to...Ch. 7.5 - Retrieve, Infer, Apply List the types of...Ch. 7.5 - Prob. 5.3CCCh. 7.5 - Prob. 5.4CCCh. 7.6 - MICRO INQUIRY What biomolecules make up the...Ch. 7.6 - Prob. 1CCCh. 7.6 - Prob. 2CCCh. 7.6 - Prob. 3CCCh. 7.6 - Retrieve, Infer, Apply What is quorum sensing?...Ch. 7.6 - Retrieve, Infer, Apply How is the communication...Ch. 7.7 - Prob. 1CCCh. 7.7 - What are peptones, yeast extract, beef extract,...Ch. 7.7 - Retrieve, Infer, Apply Describe four ways in which...Ch. 7.7 - What are pure cultures and why are they important?...Ch. 7.7 - Retrieve, Infer, Apply It is known that microbial...Ch. 7.7 - Retrieve, Infer, Apply How might an enrichment...Ch. 7.8 - Why is it important to have no more than about 250...Ch. 7.8 - Briefly describe each technique by which microbial...Ch. 7.8 - Prob. 2CCCh. 7.8 - Prob. 3CCCh. 7.8 - For each of the following, which enumeration...Ch. 7.9 - Prob. 1MICh. 7.9 - Prob. 1CCCh. 7.9 - Prob. 2CCCh. 7.9 - Prob. 3CCCh. 7 - Prob. 1RCCh. 7 - Prob. 2RCCh. 7 - Prob. 3RCCh. 7 - Prob. 4RCCh. 7 - Prob. 5RCCh. 7 - Prob. 6RCCh. 7 - As an alternative to diffusible signals, suggest...Ch. 7 - If you wished to obtain a pure culture of bacteria...Ch. 7 - Prob. 3ALCh. 7 - Suggest one specific mechanism underlying the...Ch. 7 - Consider cell-cell communication: bacteria that...Ch. 7 - Suppose you discovered a new bacterial strain from...Ch. 7 - Prob. 7ALCh. 7 - Prob. 8ALCh. 7 - Prob. 9AL
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