Microbiology: An Evolving Science (Fourth Edition)
Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 7.2, Problem 3TQ
Summary Introduction

To review:

The reason behind the visibility of nalidixic acid-resistant cells even after containing the mutation in gyrA.

Introduction:

The enzyme that changes the supercoiling of the deoxyribonucleic acid (DNA) or regulates the supercoiling level in DNA (deoxyribonucleic acid) is known as topoisomerase. There are two types of topoisomerase present in a cell, topoisomerase I and topoisomerase II. Type I topoisomerase enzymes function by creating transient a single-stranded breaks while type II introduces transient double-stranded breaks.

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