EBK BIOLOGY
5th Edition
ISBN: 8220101337627
Author: Maier
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 7, Problem 9GP
The allele BRCA2 was identified in families with unusually high rates of breast and ovarian cancer. Up to 80% of women with one copy of the BRCA2 allele develop one of these cancers in their lifetime.
a. Is BRCA2 a dominant or a recessive allele?
b. How is BRCA2 different from the typical pattern of
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
15. The following pedigree shows inheritance of Huntington's disease, a fatal genetic
disorder that causes neurodegeneration. Since signs and symptoms usually do not
appear until adulthood, many who are carriers may not realize their risk of passing on
the disease-causing allele. The following pedigree represents a family in which some
people are affected by Huntington's disease.
Reeessive Trit
er btmnt be
Mec
yplicalty
Hinhetee
In the snail Limnaea peregra, coiling of the shell is determined by the genes D for right-handed coiled shells, and d for left-handed coiled shells. The gene for the right-handed shell is dominant. However, the direction of coiling in any single individual is determined by the genotype of the maternal parent producing the egg, regardless of the progeny's genotype. Which describes this type of inheritance?
A. infectious heredity
B. maternal effect
C. dominant X-linked
D. organelle heredity
This pedigree traces the inheritance of a rare disease in humans.
a. Based on this pedigree, is the allele for this disease dominant or recessive? Explain.
b. What genotypes are possible for the individuals labeled 1, 2, and 3?
Chapter 7 Solutions
EBK BIOLOGY
Ch. 7 - What is the relationship between genotype and...Ch. 7 - Prob. 2LTBCh. 7 - Prob. 3LTBCh. 7 - Prob. 4LTBCh. 7 - Prob. 5LTBCh. 7 - Scientists have recently developed a process by...Ch. 7 - What is the physical basis for the independent...Ch. 7 - Prob. 8LTBCh. 7 - Prob. 9LTBCh. 7 - Prob. 10LTB
Ch. 7 - Prob. 1GPCh. 7 - Prob. 2GPCh. 7 - Prob. 3GPCh. 7 - Prob. 4GPCh. 7 - Pfeiffer syndrome is a dominant genetic disease...Ch. 7 - Prob. 6GPCh. 7 - A cross between a pea plant that produces round...Ch. 7 - Prob. 8GPCh. 7 - The allele BRCA2 was identified in families with...Ch. 7 - Two parents both have brown eyes, but they have...Ch. 7 - Prob. 2AAATBCh. 7 - Prob. 3AAATBCh. 7 - Prob. 1CTSCh. 7 - Prob. 2CTSCh. 7 - Prob. 3CTS
Additional Science Textbook Solutions
Find more solutions based on key concepts
How does the removal of hydrogen atoms from nutrient molecules result in a loss of energy from the nutrient mol...
SEELEY'S ANATOMY+PHYSIOLOGY
Gregor Mendel never saw a gene, yet he concluded that some inherited factors were responsible for the patterns ...
Campbell Essential Biology (7th Edition)
To test your knowledge, discuss the following topics with a study partner or in writing ideally from memory. Th...
HUMAN ANATOMY
On what molecule does the anticodon appear? Explain the role of this molecule in protein synthesis.
Human Physiology: An Integrated Approach (8th Edition)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Duchenne muscular dystrophy is sex linked and usually affects only males. Victims of the disease become progressively weaker, starting early in life.a. What is the probability that a woman whose brother has Duchenne’s disease will have an affected child?b. If your mother’s brother (your uncle) had Duchenne’s disease, what is the probability that you have received the allele?c. If your father’s brother had the disease, what is the probability that you have received the allele?arrow_forwardSickle cell anemia is an inherited red blood cell disorder in which there are not enough healthy red blood cells to carry oxygen throughout the body. The allele that causes sickle-cell anemia is autosomal recessive (s), and the dominant allele can be represented by S. How many offspring will be affected by the disorder if the mother is a carrier, and the father appears to be normal? (Include the gender) a. b. How many will become carriers? (include the gender) A- 三三三 四 四 II !!arrow_forwardAchondroplasia is a form of dwarfism in humans. It is caused by a mutant allele of the fibroblast growth factor receptor 3 gene ( FGFR3) that produces an overactive protein. Having one copy of the mutant allele results in dwarfism. Two copies of the mutant allele results in death before birth. The mutant FGFR3 allele is completely penetrant. 1. What can you infer about the inheritance of the FGFR alleles? A) The mutant FGFR3 allele is pleiotropic. B) Some achondroplastic dwarfs are heterozygous for the mutant allele and some are homozygous. C) The wild-type and mutant FGFR3 alleles are codominant. D) The mutant FGFR3 allele shows incomplete penetrance. 2. If two people with achondroplasia have a child together, what is the probability that their child will also have achondroplasia? A)0 B)1/2 C)2/3 D) 3/4 E)1arrow_forward
- Tay–Sachs disease is caused by recessive alleles on anautosome. In which case(s) could two parents with anormal phenotype have a child with Tay–Sachs?a. Both parents are homozygous for a Tay–Sachs allele.b. Both parents are heterozygous for a Tay–Sachsallele.c. One parent is homozygous for a Tay–Sachs allele,and the other is heterozygous.arrow_forwardColor blindness in humans is controlled by an X-linked completely recessive allele (Xc), while breast cancer is controlled by an autosomal completely dominant allele, B. A color blind male, who is a heterozygote carrier for breast cancer has three children/n with a normal eyed female (whose mother was color blind), who is homozygote recessive for the breast cancer allele. What is the probability that out of three children, 2 will be color blind males, and not show breast cancer, and one will be a color blind female, who shows breast cancer?arrow_forwardIn 1995, doctors reported a Chinese family in whichretinitis pigmentosa (progressive degeneration of theretina leading to blindness) affected only males. Allsix sons of affected males were affected, but all of thefive daughters of affected males (and all of thechildren of these daughters) were unaffected.a. What is the likelihood that this form of retinitispigmentosa is due to an autosomal mutationshowing complete dominance?b. What other possibilities could explain the inheritance of retinitis pigmentosa in this family? Whichof these possibilities do you think is most likely?arrow_forward
- Ectrodactyly is a rare condition in which the fingers are absent and the hand is split. This condition is usually inherited as an autosomal dominant trait. Ademar Freire-Maia reported the appearance of ectrodactyly in a family in São Paulo, Brazil, whose pedigree is shown here. Is this pedigree consistent with autosomal dominant inheritance? If not, what mode of inheritance is most likely? Explain your reasoning.arrow_forwardEctrodactyly is a rare condition in which the fingers are absent and the hand is split. This condition is usually inherited as an autosomal dominant trait. Ademar Freire-Maia reported the appearance of ectrodactyly in a family in São Paulo, Brazil, whose pedigree is shown here. Is this pedigree consistent with autosomal dominant inheritance? If not, what mode of inheritance is most likely? Explain your reasoning.arrow_forwardTay-Sachs disease is a rare human disease in which toxic substances accumulate in nerve cells. The recessive allele responsible for the disease is inherited in a simple Mendelian manner. For unknown reasons, the allele is more common in populations of Ashkenazi Jews of eastern Europe. A woman is planning to marry her first cousin, but the couple discovers that their shared grandfather’s sister died in infancy of Tay-Sachs disease.a. Draw the relevant parts of the pedigree, and show all the genotypes as completely as possible. b. What is the probability that the cousins’ first child will have Tay-Sachs disease, assuming that all people who marry into the family are homozygous normal?arrow_forward
- In humans, the genes for coloblindedness and hemophilia re both located on the X chromosome with no corresponding gene in the Y. These are both recessive alleles. a. If a man and a woman, both with normal vision, marry and have a colorblind son, draw the Punnet square that illustrates this. b. If the man dies and the woman remarries to a colorblind man, draw a Punnet Square showing the type of children could be expected from hre second marriage. How many/what percentages of each could ne expectedarrow_forwardRetinitis pigmentosa, a form of blindness in man, maybe caused either by a dominant autosomal gene R, or a recessive autosomal gene a. An afflicted man whose parents are both normal marries a woman with genotype AaRr. a. What proportion of the children are expected to suffer from this affliction if R and A are inherited independently? b. If this couple want to have normal children only, what isthe probability of having normal children?arrow_forwardIn humans, the genetic disease cystic fibrosis is caused by a recessive allele (a). The normal (healthy) allele is dominant (A). What is the genotype of someone who has cystic fibrosis? What are the two different genotypes that a healthy person could have? If two people were both heterozygous for the cystic fibrosis gene, what fraction of their children would be likely to have this disease? Hint: Draw a Punnett square to figure it out.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Concepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax College
Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Concepts of Biology
Biology
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:OpenStax College
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
How to solve genetics probability problems; Author: Shomu's Biology;https://www.youtube.com/watch?v=R0yjfb1ooUs;License: Standard YouTube License, CC-BY
Beyond Mendelian Genetics: Complex Patterns of Inheritance; Author: Professor Dave Explains;https://www.youtube.com/watch?v=-EmvmBuK-B8;License: Standard YouTube License, CC-BY