FUNDAMENTALS OF BIOCHEMISTRY-ACCESS
5th Edition
ISBN: 9781119498742
Author: Voet
Publisher: WILEY
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Chapter 7, Problem 9E
Summary Introduction
To explain: Whether “Hemoglobin S homozygotes who are severely anemic often have elevated levels of BPG in their erythrocytes” is beneficial or not.
Concept introduction: Sickle cell disease is an autosomal recessive disorder that results in a type of anemia known as sickle cell anemia. The sickle cell disease is characterized by the HbS/HbS homozygous allele.
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Chapter 7 Solutions
FUNDAMENTALS OF BIOCHEMISTRY-ACCESS
Ch. 7 - Prob. 1ECh. 7 - 2. Which set of binding data is likely to...Ch. 7 - Prob. 3ECh. 7 - Prob. 4ECh. 7 - 5. Drinking a few drops of a commercial...Ch. 7 - 6. Explain why long-distance runners prefer to...Ch. 7 - Prob. 7ECh. 7 - Prob. 8ECh. 7 - Prob. 9ECh. 7 - 10. In the variant hemoglobin C, glutamate at...
Ch. 7 - 11. Is myosin a fibrous protein or a globular...Ch. 7 - 12. In striated muscle, cells undergo mitosis...Ch. 7 - 13. A myosin head can undergo five ATP hydrolysis...Ch. 7 - 14. Rigor mortis, the stifle rung of muscles after...Ch. 7 - Prob. 15ECh. 7 - 16. Antibodies are well suited for recognizing...Ch. 7 - 17. Give the approximate molecular masses of an...Ch. 7 - 18. Many fish produce a tetrameric IgM. If each H...Ch. 7 - 19. Explain why the variation in VL and VH domains...Ch. 7 - 20. How many hypervariable loops are present in...Ch. 7 - Prob. 21CQCh. 7 - 22. If myoglobin had the same p50 value as...Ch. 7 - Prob. 23CQCh. 7 - Prob. 24CQCh. 7 - Prob. 25CQCh. 7 - Prob. 26CQCh. 7 - Prob. 27CQCh. 7 - Prob. 28CQCh. 7 - 29. Explain why a microfilament is polar, whereas...Ch. 7 - Prob. 30CQCh. 7 - Prob. 31CQCh. 7 - Prob. 32CQCh. 7 - Prob. 33CQCh. 7 - Prob. 34CQCh. 7 - MORE TO EXPLORE (a) Lock up information about...
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- A reverse phase column chromatography separates proteins according to their polarity. Which pentapeptide will be eluted FIRST when chromatographed at pH 7 using a reverse phase column such as a C-18 column? Peptide Sequence (from N-terminal to C-terminal) AKGED GAAVF ALLLI MCYAG GAAVF MCYAG ALLLI AKGEDarrow_forwardMelting of three DNA samples with varying lengths was monitored by increase of ultraviolet light absorbance at 260 nm. Which is the shortest DNA? A B Carrow_forwardSelect the CORRECT description of the peptide bond. The peptide bond can freely rotate around the peptide bond. The peptide bond is non-polar, hydrophobic and does not have a dipole. The peptide bond is most stable in the cis configuration. The peptide bond is rigid and planar. The peptide bond has a mix of single and double bond characters. The peptide bond is most stable in the trans configuration.arrow_forward
- Below is a fractional saturation curve for O2 binding to adult hemoglobin. Assume that curve Y represents a system at pH 7.4 and with a normal physiological level of 2,3-BPG. Curve Z represents a system that ___________________ Curve Z: is at pH 7.4 with a higher than normal physiological level of 2,3-BPG. is at pH 7.4 with a normal physiological level of 2,3-BPG but with a decreased level of CO2. has a higher pH with a normal physiological level of 2,3-BPG. has a higher pH with a lower than physiological level of 2,3-BPG.arrow_forwardWhich is a homotropic positive effector of aspartate transcarbamoylase (ATCase)? oxygen CTP aspartate ATParrow_forwardThe reaction scheme shows the mechanism of chymotrypsin-catalyzed peptide hydrolysis. Select ALL CORRECT statements regarding the chymotrypsin mechanism. Serine is the nucleophile in the step 3. Histidine is a general base in the step 2. Carbonyl carbon is the electrophile in the step 3. Histidine is a general acid in the step 4. Carbonyl carbon is the nucleophile in the step 3. This is an example of covalent catalysis. Aspartate is the electrophile in the step 3. Histidine is the nucleophile in the step 3.arrow_forward
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