Chapter 7, Problem 7.65AP

Interpretation Introduction

Interpretation:

The validation of the statement, “The energy difference between $cis\text{-}$ and $trans\text{-}1,3\text{-}di\text{-}tert\text{-butylcyclohexane}$ is a good approximation for the energy difference between the chair and twist-boat forms of cyclohexane” is to be stated.

Concept introduction:

In the boat conformation, if the bulky groups are present at the axial positions then the compound becomes unstable as it experiences van der Waals repulsion known as 1, 3-diaxial van der Waals repulsion. The compound undergoes a conformational change from boat conformation to twist-boat conformation to reduce the strain and becomes stable.