EBK BIOLOGY
EBK BIOLOGY
5th Edition
ISBN: 9780133996807
Author: Maier
Publisher: PEARSON CUSTOM PUB.(CONSIGNMENT)
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Chapter 7, Problem 5GP

Pfeiffer syndrome is a dominant genetic disease that occurs when certain bones in the skull fuse too early in the development of a child, leading to distorted head and face shape. If a man heterozygous for the allele that causes Pfeiffer syndrome marries a woman who is homozygous for the nonmutant allele, what is the chance that their first child will have this syndrome?

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Bob and Joan know from a blood test that they are each heterozygous (carriers) for the autosomal recessive gene that causes sickle cell disease. If their first three children are healthy, what is the probability that their fourth child will have the disease?
Hemophilia is a sex-linked recessive trait. A male hemophiliac and phenotypically normal female have a son with hemophilia.  They would like to have one more child. What is the probability of having a child without hemophilia? Explain using a Punnett square.   Is it possible for a girl to be born with hemophilia? Explain.
For a recessive condition, two normal heterozygous individuals have children. What is the likelihood of their children being affected by this condition? What is the likelihood of their children being carriers without the condition? What is the likelihood of their asymptomatic children being carriers? Suppose that an individual with the condition has children with a heterozygous individual, what is the likelihood of their children being carriers?
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