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EBK HUMAN PHYSIOLOGY
15th Edition
ISBN: 9781260163049
Author: Fox
Publisher: MCGRAW HILL BOOK COMPANY
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Question
Chapter 7, Problem 33RA
Summary Introduction
To review:
The scientific investigations that indicate the relationship between alcoholism and a particular allele for D2 dopamine receptor.
Introduction:
Dopamine receptors are included in the G-protein-coupled receptor class and they are prominent in the central nervous system. The dopamine receptors activate various effectors by the signaling of different protein interactions. These are involved in many neurological processes such as memory, learning, cognition, motor control, and so on.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 7 Solutions
EBK HUMAN PHYSIOLOGY
Ch. 7 - Draw a neuron, label its parts, and describe the...Ch. 7 - Distinguish between sensory neurons, motor...Ch. 7 - Describe the structure of the neurilemma, and...Ch. 7 - Explain how myelin sheaths are formed in the CNS....Ch. 7 - Explain what is meant by the blood-brain barrier....Ch. 7 - Define the terms depolarization and...Ch. 7 - Prob. 4bCPCh. 7 - Describe how gating of Na+andK+ in the axon...Ch. 7 - Prob. 5aCPCh. 7 - Prob. 5bCP
Ch. 7 - Prob. 6aCPCh. 7 - Describe the location of neurotransmitters within...Ch. 7 - Describe the sequence of events by which action...Ch. 7 - Explain how chemically regulated channels differ...Ch. 7 - Prob. 8CPCh. 7 - Prob. 9aCPCh. 7 - Prob. 9bCPCh. 7 - Prob. 10CPCh. 7 - Prob. 11CPCh. 7 - Prob. 12aCPCh. 7 - Prob. 12bCPCh. 7 - Prob. 13aCPCh. 7 - Prob. 13bCPCh. 7 - Prob. 14aCPCh. 7 - Describe the mechanism of action of glycine and...Ch. 7 - Give examples of endogenous opioid polypeptides,...Ch. 7 - Prob. 15bCPCh. 7 - Prob. 16CPCh. 7 - Prob. 17aCPCh. 7 - Prob. 17bCPCh. 7 - Prob. 17cCPCh. 7 - Prob. 1RACh. 7 - Prob. 2RACh. 7 - Prob. 3RACh. 7 - Prob. 4RACh. 7 - Repolarization of an axon during an action...Ch. 7 - As the strength of a depolarizing stimulus to an...Ch. 7 - Prob. 7RACh. 7 - Which of these is not a characteristic of synaptic...Ch. 7 - Prob. 9RACh. 7 - Prob. 10RACh. 7 - Prob. 11RACh. 7 - Prob. 12RACh. 7 - Prob. 13RACh. 7 - Prob. 14RACh. 7 - Prob. 15RACh. 7 - Prob. 16RACh. 7 - Prob. 17RACh. 7 - Which of these may be produced by the action of...Ch. 7 - Prob. 19RACh. 7 - In a step-by-step manner, explain how the...Ch. 7 - Prob. 21RACh. 7 - Prob. 22RACh. 7 - Prob. 23RACh. 7 - Prob. 24RACh. 7 - Once an EPSP is produced in a dendrite, how does...Ch. 7 - Prob. 26RACh. 7 - List the endogenous opioids in the brain and...Ch. 7 - Explain what is meant by long-term potentiation...Ch. 7 - Prob. 29RACh. 7 - Prob. 30RACh. 7 - Prob. 31RACh. 7 - Prob. 32RACh. 7 - Prob. 33RACh. 7 - Explain the nature of the endocannabinoids....Ch. 7 - Prob. 35RACh. 7 - Prob. 36RACh. 7 - Prob. 37RACh. 7 - Prob. 38RACh. 7 - Prob. 39RACh. 7 - Use the figure below (from figure 7.34) to answer...
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