EBK HUMAN PHYSIOLOGY
EBK HUMAN PHYSIOLOGY
8th Edition
ISBN: 9780134704227
Author: Silverthorn
Publisher: YUZU
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Chapter 7, Problem 30RQ
Summary Introduction

To determine: The half-life of a drug based on the information given in the graph.

Introduction: A drug is a medicine or any other substance that shows a physiological effect when introduced to the body. A drug can be inhaled, injected, smoked, consumed, absorbed by the skin, and dissolved under the tongue.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

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EBK HUMAN PHYSIOLOGY

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