Cardiopulmonary Anatomy & Physiology
Cardiopulmonary Anatomy & Physiology
7th Edition
ISBN: 9781337794909
Author: Des Jardins, Terry.
Publisher: Cengage Learning,
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Chapter 7, Problem 10RQ
Summary Introduction

Introduction:

In biochemical reactions, the Henderson–Hasselbalch equation can be used to determine the pH (potential of hydrogen) of a buffer solution, when the concentration of the acid and that of its conjugate base are given.

H-AH++Aacid                 base

logKa=log[H+]+log([A]/[HA])pKa=pH=log([A]/[HA])therefore,pH=pKa+log[(ionized/unionized)]

Thus, the Henderson–Hasselbalch equation applied during normal conditions in the blood is,

pH=pK+log[HCO3][PCO2×0.03]

This equation helps to calculate bicarbonate ion concentration.

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