EBK BIOLOGY
EBK BIOLOGY
6th Edition
ISBN: 9780134819150
Author: Maier
Publisher: VST
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Chapter 6, Problem 9LTB
Summary Introduction

Introduction:

Interphase is a phase which takes place before and after mitosis of the cell cycle, i.e., between two mitotic divisions. Interphase contains three different phases which are G1, S and G2.

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Draw and label G1 and G2 stages of interphase and each stage of mitosis (in order) for a cell that has two large and two small chromosomes, 2n=4. For unreplicated chromosome draw a line ( / ) and for replicated chromosome draw an X. Since we are focusing on the DNA, you can skip drawing the nuclear membrane or spindle fibers. For simplicity, do not indicate that the chromosomes are decondensed chromatin during interphase.  Mark and label a place on one of the large chromosomes with the dominant allele of the “A” gene and put the recessive allele “a” on the other homolog. Mark and label a place on one of the small chromosomes with allele “B” and put the recessive allele “b” on the other homolog.
The following diagram is meant to help you understand how the amount of DNA in a cell changes as the cell cycle progresses. On the diagram, identify two of the stages of the cell cycle being described and identify how much DNA exists per cell, where a cell is defined as a distinct nucleus. Note that the sequence of images highlights one of the chromosomes of the cell. The other chromosomes, while also present, are faded in the background. Stage in Cell Cycle: A Status of Chromosomes: (Only one of the chromosomes is intensely colored) NANA INNNNNNN wwwww wwwNYA wwwww WXXXX VANNNNNN www Amount of DNA Per Cell: C NNNNA NNNNNN WWXXXXX NNNNNNE WNNNN www B NNNNN Between 1X and 2X 2X D 1X
Mitotic nondisjunction can occur, particularly in tumor cells. Assume a single nondisjunction event involving the X chromosome occurs in a cell undergoing mitosis in a human female. First, consider the daughter cell with the smaller number of chromosomes: How many total chromosomes will this cell have?  How many X chromosomes will this cell have?    Next, consider the daughter cell with the larger number of chromosomes: How many total chromosomes will this cell have?  How many X chromosomes will this cell have?
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