Human Biology (MindTap Course List)
11th Edition
ISBN: 9781305112100
Author: Cecie Starr, Beverly McMillan
Publisher: Cengage Learning
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Chapter 6, Problem 6RQ
Explain why (a) calcium ions and (b) ACh are vital for muscle contraction.
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. Consider a base substitution mutation that occurred in a DNA sequence that resulted in a change in the
encoded protein from the amino acid glutamic acid to aspartic acid. Normally the glutamic acid amino acid
is located on the outside of the soluble protein but not near an active site.
O-H¨
A. What type of mutation occurred?
O-H
B. What 2 types of chemical bonds are found in the R-groups
of each amino acid? The R groups are shaded.
CH2
CH2
CH2
H2N-C-COOH
H2N-C-COOH
1
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H
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D. Consider the chemical properties of the two amino acids and the location of the amino acid in the
protein. Explain what effect this mutation will have on this protein's function and why.
engineered constructs that consist of hollow fibers are acting as synthetic capillaries, around which cells have been loaded. The cellular space around a single fiber can be modeled as if it were a Krogh tissue cylinder. Each fiber has an outside “capillary” radius of 100 µm and the “tissue” radius can be taken as 200 µm. The following values apply to the device:R0 = 20 µM/secaO2 = 1.35 µM/mmHgDO2,T = 1.67 x 10-5 cm2/secPO2,m = 4 x 10-3 cm/secInstead of blood inside the fibers, the oxygen transport and tissue consumption are being investigated by usingan aqueous solution saturated with pure oxygen. As a result, there is no mass transfer resistance in the synthetic“capillary”, only that due to the membrane itself. Rather than accounting for pO2 variations along the length ofthe fiber, use an average value in the “capillary” of 130 mmHg.Is the tissue fully oxygenated?
Molecular Biology
Please help with question. thank you
You are studying the expression of the lac operon. You have isolated mutants as described below. In the presence of glucose, explain/describe what would happen, for each mutant, to the expression of the lac operon when you add lactose AND what would happen when the bacteria has used up all of the lactose (if the mutant is able to use lactose).5. Mutations in the lac operator that strengthen the binding of the lac repressor 200 fold
6. Mutations in the promoter that prevent binding of RNA polymerase
7. Mutations in CRP/CAP protein that prevent binding of cAMP8. Mutations in sigma factor that prevent binding of sigma to core RNA polymerase
Chapter 6 Solutions
Human Biology (MindTap Course List)
Ch. 6 - In a general sense, how do skeletal muscles...Ch. 6 - In the diagram below, label the fine structure of...Ch. 6 - How do actin and myosin interact in a sarcomere to...Ch. 6 - How does a muscle fiber incur an oxygen debt?Ch. 6 - What is the function of the sarcoplasmic reticulum...Ch. 6 - Explain why (a) calcium ions and (b) ACh are vital...Ch. 6 - What is a motor unit? Why does a rapid series of...Ch. 6 - What are the structural and functional differences...Ch. 6 - Prob. 1SQCh. 6 - Prob. 2SQ
Ch. 6 - Prob. 3SQCh. 6 - The _____ is the basic unit of muscle contraction....Ch. 6 - Skeletal muscle contraction requires _________. a....Ch. 6 - Nerve impulses first stimulate a skeletal muscle...Ch. 6 - Prob. 7SQCh. 6 - Prob. 8SQCh. 6 - Prob. 9SQCh. 6 - Prob. 10SQCh. 6 - You are training athletes for the 100-meter dash....Ch. 6 - Prob. 2CTCh. 6 - Prob. 3CTCh. 6 - At the gym Sean gets on a stair-climbing machine...
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