An Arrhenius plot has to be plotted for the conversion of cyclopropane to propene and the activation energy for the reaction has to be calculated. Concept Introduction: Activation energy: It is defined as the minimum energy required by the reacting species in order to undergo chemical reaction . Activation energy can be represented as E a . The unit of activation energy is kJ/mol . Catalyst: The catalyst is a chemical substance that increases the rate of the reaction without participating in the reaction by reducing the activation energy of the reaction. Arrhenius equation: Arrhenius equation is a formula that represents the temperature dependence of reaction rates The Arrhenius equation has to be represented as follows K = A e − E a / R T E a represents the activation energy and it’s unit is kJ/mol R represents the universal gas constant and it has the value of 8 .314 J/K .mol T represents the absolute temperature K represents the frequency factor or collision frequency

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Liquid chromatography has been used to track the concentration of remdesivir (a broad-spectrum antiviral drug, structure shown at right) in COVID patients undergoing experimental treatments. Intensity The authors provide the following details regarding standard solutions preparation: HN CN HO OH NH2 Remdesivir (RDV) stock solution (5000 µg/mL) was prepared by dissolving RDV drug powder using the mixture of DMSO: MeOH (30:70 v/v). The RDV working standard solutions for calibration and quality controls were prepared using methanol in concentrations of 100, 10, 1, 0.1, 0.01 µg/mL. 1, 2.5, 5, 7.5, 10, 25, 50, 75, 100, 250, 500, 1000, and 5000 ng/mL sample solutions were prepared freshly by spiking calibration standard solutions into the blank human plasma samples for method calibration. a) What type of calibration method is being described? Why do you think the authors chose this method as opposed to another? b) Based on the details provided in part a, describe an appropriate method blank…

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Chapter 6, Problem 6.10P

Interpretation Introduction

Interpretation:

An Arrhenius plot has to be plotted for the conversion of cyclopropane to propene and the activation energy for the reaction has to be calculated.

Concept Introduction:

Activation energy: It is defined as the minimum energy required by the reacting species in order to undergo chemical reaction.

Activation energy can be represented as Ea. The unit of activation energy is kJ/mol.

Catalyst: The catalyst is a chemical substance that increases the rate of the reaction without participating in the reaction by reducing the activation energy of the reaction.

Arrhenius equation:

Arrhenius equation is a formula that represents the temperature dependence of reaction rates

The Arrhenius equation has to be represented as follows

K = Ae−Ea/RT

Ea represents the activation energy and it’s unit is kJ/mol

R represents the universal gas constant and it has the value of 8.314 J/K.mol

T represents the absolute temperature

K represents the frequency factor or collision frequency

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