BIOLOGY 2E
BIOLOGY 2E
2nd Edition
ISBN: 9781506699851
Author: OpenStax
Publisher: XANEDU PUBLISHING
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Chapter 6, Problem 3VCQ

Figure 6.14 The hydrolysis of one ATP molecule releases 7.3 kcal/mol of energy (?G = -7.3 kcal/mol of energy). If it takes 2.1 kcal/mol of energy to move

one Na+ across the membrane (?G = +2.1 kcal/mol of energy), how many sodium ions could be moved by the hydrolysis of one ATP molecule?

Chapter 6, Problem 3VCQ, Figure 6.14 The hydrolysis of one ATP molecule releases 7.3 kcal/mol of energy (?G = -7.3 kcal/mol

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In the following situations, what is the free energy change if 1 mole of Na+is transported across a membrane from a region where the concentration is1 μM to a region where it is 100 mM?(Assume T = 37 °C.) (a) In the absence of a membrane potential. (b) When the transport is opposed by a membrane potential of 70 mV. (c) In each case, will hydrolysis of 1 mole of ATP suffice to drive the transport of 1 mole of ion, assuming pH 7.4 and the following cytoplasmic concentrations: ATP = 4.60 mM, Pi = 5.10 mM, ADP = 310 μM?
Each proton that moves across the membrane releases about 14 kJ/mol of energy. Given that ATP requires 30.5 kJ/mol of energy to form, how many protons cross the membrane per ATP synthesized?  (Hint: can you have half a proton?)
You know that the free energy of ATP hydrolysis depends on the ATP/ADP ratio.  Given that under standard conditions DGo = -30.5 kJ/mol, what should be DG of ATP hydrolysis under normal intracellular concentrations? [ATP] = 2.3 mM,     [ADP] = 0.25 mM,        [Pi] = 1.65 mM   What is the energy of ATP hydrolysis in a cell that is ATP-depleted?   [ATP] = 0.1 mM,     [ADP] = 2.8 mM,        [Pi] = 1.65 mM
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